Metal Complex - DNA Interactions Book

A Basic Structural and Kinetic Aspects

1. Sequence-Selective Binding of Transition Metal Complexes to DNA

2. Thermodynamic Models of Metal Ion -DNA.Interactions

3. Metal Ion Coordination in G-quadruplexes

4. Supramolecular Chemistry of Metal-Nucleobase Complexes

B Medical Applications

5. Platinum Drugs, Nucleotides, and DNA: the Role of Interligand Interactions,

nucleotides and DNA

6. Role of DNA Repair in Antitumor Effects of Platinum Drugs

7. Telomeres and Telomerase: Potential Targets for Platinum Complexes

8. Toward Photodynamic Therapy of Cancer with Platinum Group Metal Polyazine Complexes

9. Platinated Oligonucleotides: Synthesis and Applications for the Control of Gene

Expression

10. New Titanium and Ruthenium Anticancer Drugs and their Interaction with DNA

C DNA-Recognition - Nucleases and Sensors

11. Groove-Binding Ruthenium(II) Complexes as Probes of DNA Recognition

12. DNA Recognition and Binding by Peptide-Metal Complex conjugate

13. Artificial Restriction Agents - Hydrolytic Agents for DNA Cleavage

14. New Metallo-DNAzymes: Fundamental Studies of Metal-DNA Interactions and

Metal Sensing Applications

15. Two-metal Ion Dependent Catalysis in Nucleic Acid Enzymes

D Toxicological aspects

16. Mercury- DNA Interactions. Structural Studies on Mercury^II -Mediated T-T Base-Pair with NMR Spectroscopy

17. Chromium-Induced DNA Damage and Repair

18. Arsenic and nickel: Mechanisms Affecting DNA Integrity