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Foreword | ||
Preface | ||
Contributors | ||
1 | An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer | 1 |
Pt. I | Preclinical Antiestrogens | |
2 | Antiestrogens and the Cell Cycle | 17 |
3 | Drug Resistance to Antiestrogens | 47 |
4 | Mechanisms of Liver Carcinogenesis by Antiestrogens | 69 |
5 | The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepatocarcinogenesis in the Rat | 83 |
6 | Preclinical Studies of Raloxifene and Related Compounds | 133 |
7 | Pure Antiestrogens | 161 |
Pt. II | Antiestrogens: Clinical | |
8 | Tamoxifen for the Treatment of Breast Cancer | 185 |
9 | Clinical Utility of New Antiestrogens | 195 |
10 | Breast Cancer Prevention with Antiestrogens | 213 |
Pt. III | Inhibition of Estrogen Synthesis | |
11 | Aromatase Inhibitors | 235 |
12 | Clinical Utility of Aromatase Inhibitors | 265 |
13 | LH-RH Agonists for the Treatment of Breast Cancer: Development and Current Status | 293 |
Pt. IV | Androgens and Androgen Withdrawal | |
14 | Molecular Action of Androgens | 311 |
15 | Steroidal Antiandrogens | 325 |
16 | Nonsteroidal Antiandrogens | 347 |
17 | LH-RH Agonist Role in Prostate Cancer Management | 369 |
Pt. V | Perspective on Progress | |
18 | Recent Progress in Breast Cancer Research | 385 |
Index | 409 |
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