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Geriatric Bioscience: The Link between Aging and Disease Book

Geriatric Bioscience: The Link between Aging and Disease
Geriatric Bioscience: The Link between Aging and Disease, It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, Geriatric Bioscience: The Link between Aging and Disease has a rating of 4 stars
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Geriatric Bioscience: The Link between Aging and Disease, It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, Geriatric Bioscience: The Link between Aging and Disease
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  • Geriatric Bioscience: The Link between Aging and Disease
  • Written by author David Hamerman
  • Published by Johns Hopkins University Press, November 2007
  • It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty
  • It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty
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Authors

Foreword   Robert N. Butler     vii
Preface     ix
The Emergence and Future of Geriatrics     1
An Introduction to Concepts of Molecular Biology   E. Richard Stanley     13
Aging     25
Trends in the Aging of the Population     25
What Is Aging? Can We Distinguish between Aging and Disease?     28
Mechanisms of Aging     31
Longevity: Genetics of Extended Life Span or Risk for Adverse Events     41
Interrelations of Certain Aging-related Conditions     50
Cytokines, Inflammation, and Responses to Stress     50
Atherosclerosis: Risk Factors for Cardiovascular Disease     58
The Metabolic Syndrome and Type 2 Diabetes     64
Osteoporosis     97
Osteoarthritis     121
Frailty and Related Conditions: Anorexia, Sarcopenia, Exercise     132
Cancer     145
Alzheimer Disease   Peter Davies     155
Interactive Therapies Significant for an Aging Population     169
Cyclooxygenases     169
Statins     173
Bisphosphonates     180
Thiazolidinediones and Peroxisome Proliferator-activated Receptory [gamma]     183
CytokineInhibitors as a Landmark for Newer Anti-inflammatory Therapies     192
Hormonal Therapies     199
Preventive Gerontology     209
The Compression or Expansion of Morbidity?     209
Healthy Lifestyle Practices     211
"Successful Aging"     214
Epilogue     216
Glossary     223
References     227
Index     281


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