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List of contributors | ||
Preface | ||
Pt. 1 | Assessing and utilizing the diagnostic or prognostic power of biomarkers | |
1 | Evidence-based medicine: evaluation of biomarkers | 3 |
2 | Development of biomarkers: the industrial perspective | 16 |
3 | Statistical approaches to rational biomarker selection | 24 |
4 | Using intelligent systems in clinical decision support | 32 |
Pt. 2 | Biomarkers of kidney disease and dysfunction | |
5 | Biomarkers in renal disease | 45 |
6 | The genetics of renal disease | 56 |
7 | Early markers of nephrotoxicity for environmental and occupational monitoring | 66 |
8 | The early detection of renal impairment in diabetes mellitus. The case for microalbuminuria and other biomarkers | 76 |
Pt. 3 | Biomarkers of bone disease and dysfunction | |
9 | Bone turnover markers in clinical practice | 99 |
10 | Biomarkers of bone formation | 115 |
11 | Biochemical markers of bone resorption | 122 |
12 | The clinical application of biomarkers in osteoporosis | 133 |
13 | Sources of preanalytical variability in the measurement of biochemical markers of bone turnover | 140 |
14 | Genetic approaches to the study of complex diseases: osteoporosis | 159 |
Pt. 4 | Biomarkers of liver disease and dysfunction | |
15 | Biomarkers of hepatic disease | 167 |
16 | The immunogenetics of metabolic liver disease | 177 |
17 | Toxicogenetic markers of liver dysfunction | 190 |
18 | Prognosis and management of patients with acute liver failure | 199 |
19 | Biomarkers in artificial and bioartificial liver support | 211 |
20 | Prognostic markers in liver disease | 221 |
21 | Apoptosis: biomarkers and the key role of mitochondria | 228 |
22 | Liver regeneration: mechanisms and markers | 239 |
23 | Determinants of responses to viruses and self in liver disease | 244 |
24 | IL-6-type cytokines and signalling in inflammation | 256 |
Pt. 5 | Biomarkers of gastrointestinal disease and dysfunction | |
25 | Biomarkers in gastrointestinal disease | 265 |
26 | Tumour markers in gastrointestinal disease | 272 |
27 | Markers of malabsorption: coeliac disease | 281 |
Pt. 6 | Biomarkers in toxicology | |
28 | Genomics and biomarkers in toxicology | 291 |
29 | Protein profiling and proteomic databases | 299 |
30 | Biomarkers for evaluating the safety of genetically modified foods | 313 |
Pt. 7 | Biomarkers of cardiovascular disease and dysfunction | |
31 | The impact of biochemical tests on patient management | 325 |
32 | Cardiac natriuretic peptides in risk assessment of patients with acute myocardial infarction or congestive heart failure | 334 |
33 | Serum markers of inflammation and cardiovascular risk | 345 |
34 | The clinical significance of markers of coagulation in acute coronary syndromes | 355 |
35 | Endothelin: what does it tell us about myocardial and endothelial dysfunction? | 365 |
36 | Homocysteine: a reversible risk factor for coronary heart disease | 374 |
37 | Matrix metalloproteinases and their tissue inhibitors | 379 |
Pt. 8 | Biomarkers of neurological disease and dysfunction | |
38 | Biomarkers of neurodegenerative disorders | 391 |
39 | Traumatic brain injury: assessment by biochemical serum markers | 398 |
40 | An overview of S-100[beta] as a clinically useful biomarker of brain tissue damage | 406 |
Pt. 9 | Biomarkers in transplantation | |
41 | Monitoring heart and lung transplant patients | 415 |
42 | Monitoring liver transplant recipients | 423 |
43 | Chronic allograft damage index as a surrogate marker for chronic allograft rejection | 433 |
44 | Advances in pharmacodynamic biomarkers for monitoring the response to immunosuppressive drug therapy | 442 |
45 | The use of biomarkers for monitoring the response to immunosuppressive drug therapy | 451 |
46 | Post-transplantation bone disease | 461 |
47 | Molecular diagnosis of cytomegalovirus disease | 467 |
48 | Diagnosis and monitoring of inflammatory events in transplant recipients | 474 |
Index | 483 |
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Add Biomarkers of Disease, This new publication takes a critical, evidence-based look at the efficacy of new diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of new products being bro, Biomarkers of Disease to the inventory that you are selling on WonderClubX
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Add Biomarkers of Disease, This new publication takes a critical, evidence-based look at the efficacy of new diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of new products being bro, Biomarkers of Disease to your collection on WonderClub |