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Protein Engineering and Design Book

Protein Engineering and Design
Protein Engineering and Design, Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fie, Protein Engineering and Design has a rating of 4 stars
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Protein Engineering and Design, Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fie, Protein Engineering and Design
4 out of 5 stars based on 2 reviews
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Digital Copy
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  • Protein Engineering and Design
  • Written by author Sheldon J. Park
  • Published by Taylor & Francis, Inc., August 2009
  • Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fie
  • Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fie
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Authors

Preface vii

Editors ix

Contributor List xi

Chapter 1 Phage Display Systems for Protein Engineering Andreas Ernst Sachdev S. Sidhu 1

Chapter 2 Cell Surface Display Systems for Protein Engineering Sarah J. Moore Mark J. Olsen Jennifer R. Cochran Frank V. Cochran 23

Chapter 3 Cell-Free Display Systems for Protein Engineering Pamela A. Barendt Casim A. Sarkar 51

Chapter 4 Library Construction for Protein Engineering Daa Lipovek Marco Mena Shaun M. Lippow Subhayu Basu Brian M. Baynes 83

Chapter 5 Design and Engineering of Synthetic Binding Proteins Using Nonantibody Scaffolds Shohei Koide 109

Chapter 6 Combinatorial Enzyme Engineering Patrick C. Cirino Christopher S. Frei 131

Chapter 7 Engineering of Therapeutic Proteins Fei Wen Sheryl B. Rubin-Pitel Huimin Zhao 153

Chapter 8 Protein Engineered Biomaterials Cheryl Wong Po Foo Sarah C. Heilshorn 179

Chapter 9 Protein Engineering Using Noncanonical Amino Acids Deniz Yüksel Diren Pamuk Yulia Ivanova Krishna Kumar 205

Chapter 10 Computer Graphics, Homology Modeling, and Bioinformatics David F. Green 223

Chapter 11 Knowledge-Based Protein Design Michael A. Fisher Shona C. Patel Izhack Cherny Michael H. Hecht 239

Chapter 12 Molecular Force Fields Patrice Koehl 257

Chapter 13 Rotamer Libraries for Molecular Modeling and Design of Proteins Hidetoshi Kono 281

Chapter 14 Search Algorithms Julia M. Shifman Menachem Fromer 293

Chapter 15 Modulating Protein Structure M.S. Hanes T.M. Handel A.B. Chowdry 313

Chapter 16 Modulation of Intrinsic Properties by Computational Design Vikas Nanda Fei Xu Daniel Hsieh 327

Chapter 17 Modulating Protein Interactions by Rational and Computational Design Jonathan S. Marvin LorenL. Looger 343

Chapter 18 Future Challenges of Computational Protein Design Eun Jung Choi Gurkan Guntas Brian Kuhlman 367

Index 389


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