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Contributors | ||
Acknowledgments | ||
A Quote from 1962 | ||
Foreword | ||
Ch. 1 | Multifactor Interaction Network of Carcinogenesis - A "Tour Guide" | |
Ch. 2 | Synergism and Antagonism between Chemical Carcinogens | |
Ch. 3 | Synergism in Carcinogenesis: Mathematical Approaches to Its Evaluation | |
Ch. 4 | Inhibition of Chemical Carcinogenesis | |
Ch. 5 | Promotion and Cocarcinogenesis | |
Introduction | ||
Sect. I | Tumor Promotion in Skin | |
Sect. II | Tumor Promotion in Liver | |
Sect. IIIA | Note on Multistage Carcinogenesis in Other Organs and In Vitro | |
Sect. IIIB | Note on Tumor Promoters, Cocarcinogens, and Nongenotoxic Carcinogens | |
Ch. 6 | Computerized Data Management as a Tool to Study Combination Effects in Carcinogenesis | |
Ch. 7 | Intercellular Communication: A Paradigm for the Interpretation of the Initiation/Promotion/Progression Model of Carcinogenesis | |
App. Chemical Cancerogenesis: Definitions of Frequently Used Terms | ||
Ch. 8 | Immunotoxicology of Chemical Carcinogens | |
Ch. 9 | The Effect of Diet on Tumor Induction | |
Sect. I | Effect of Caloric (Energy) Restriction | |
Sect. II | Modulation by Protein and Individual Amino Acids | |
Sect. III | Modulation by Vitamins | |
Sect. IV | Modulation by Minerals | |
Sect. V | Dietary Fiber and Its Effect on Cancer Incidence | |
Editors' Note I to Chapter 9: Indirect Modification of Chemical Carcinogenesis by Nutritional Factors Through Regulation of the Mixed-Function Oxidase System | ||
Editors' Note II to Chapter 9: On Evidence for Preventive Significance of Dietary Supplementation | ||
Ch. 10 | The Effect of Animal Age on Tumor Induction | |
Ch. 11 | The Effect of Hormones on Tumor Induction | |
Sect. I | Brief Overview of the Endocrine System | |
Sect. II | Hormonal Carcinogenesis | |
Sect. III | Effect of Hormones on Carcinogenesis by Nonhormone Chemical Agents | |
Editors' Note Added in Proof: On the Significance of Environmental Xenoestrogens | ||
Ch. 12 | Effect of Genetic Susceptibility on Tumor Induction | |
Ch. 13 | Radiation Injury and Radiation Carcinogenesis with Special Reference to Combination Effects with Chemical Agents | |
Ch. 14 | Mechanisms of Viral Tumorigenesis and the Combination Effects of Viruses and Chemical Carcinogens | |
Sect. I | General Characteristics of Tumor Viruses. Viral and Cellular Oncogenes. Nonviral Oncogene Activators | |
Sect. II | Molecular Biology of Virally-Induced Cell Transformation and Tumorigenesis | |
Sect. III | Viral-Chemical Combination Effects in Tumorigenesis | |
Speculative Closing Note | ||
Ch. 15 | Effect of Stress on Tumor Induction | |
Editors' Note Added in Proof: Stress Proteins: Heat-Shock Proteins/Molecular Chaperones | ||
Ch. 16 | Extremely Low Frequency Electromagnetic Fields and Cancer | |
Postscriptum: An Editor's Musings | ||
Index |
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