Forensic DNA Typing: Biology, Technology, and Genetics of STR Markers Book

1	Overview and history of DNA typing	1
2	DNA biology review	17
3	Sample collection, DNA extraction and DNA quantitation	33
4	The polymerase chain reaction (DNA amplification)	63
5	Commonly used short tandem repeat markers and commercial kits	85
6	Biology of STRs : stutter products, non-template addition, microvariants, null alleles and mutation rates	123
7	Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number	145
8	Single nucleotide polymorphisms and other bi-allelic markers	181
9	Y chromosome DNA testing	201
10	Mitochondrial DNA analysis	241
11	Non-human DNA testing and microbial forensics	299
12	DNA separation methods : slab gel and capillary electrophoresis	313
13	DNA detection methods : fluorescent dyes and silver-staining	325
14	Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems	345
15	STR genotyping issues	373
16	Laboratory validation	389
17	New technologies, automation, and expert systems	413
18	Combined DNA index system (CODIS) and the use of DNA databases	435
19	Basic genetic principles, statistics, and probability	455
20	STR population database analyses	473
21	Profile frequency estimates, likelihood ratios, and source attribution	497
22	Approaches to statistical analysis of mixtures and degraded DNA	519
23	Kinship and parentage testing	529
24	Mass disaster DNA victim identification	541
App. I	Reported STR alleles : sizes and sequences	561
App. II	U.S. population data - STR allele frequencies	577
App. III	Suppliers of DNA analysis equipment, products, OR services	585
App. IV	DNA advisory board quality assurance standards	593
App. V	DAB recommendations on statistics	613
App. VI	NRC II recommendations	623
App. VII	Example DNA cases	627