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Preface | ||
1 | Overview of Viruses and Virus Infection | |
Classification of Viruses | 5 | |
An Overview of the Replication Cycle of Viruses | 8 | |
Effects of Virus Infection on the Host Cell | 27 | |
Epidemiology: The Spread of Viruses from Person to Person | 29 | |
2 | The Structure of Viruses | |
Helical Symmetry | 33 | |
Icosahedral Symmetry | 34 | |
Nonenveloped Viruses with More Complicated Structural Features | 43 | |
Enveloped Viruses | 43 | |
Assembly of Virions | 52 | |
Stability of Virions | 55 | |
3 | Plus-Strand RNA and Double-Strand RNA Viruses | |
Family Picornaviridae | 58 | |
Family Caliciviridae | 71 | |
Family Astroviridae | 74 | |
Family Togaviridae | 76 | |
Family Flaviviridae | 85 | |
Family Coronaviridae | 100 | |
Family Arteriviridae | 103 | |
The Plus-Strand RNA Viruses of Plants | 104 | |
Origin and Evolution of Plus-Strand RNA Viruses | 105 | |
Viruses That Contain Double-Stranded RNA: Family Reoviridae | 108 | |
4 | Minus-Strand RNA Viruses | |
Overview of the Minus-Strand RNA Viruses | 123 | |
Family Rhabdoviridae | 126 | |
Family Paramyxoviridae | 132 | |
Family Filoviridae | 144 | |
Family Bornaviridae | 146 | |
Family Orthomyxoviridae | 147 | |
Family Bunyaviridae | 156 | |
Family Arenaviridae | 162 | |
Evolution of Minus-Strand RNA Viruses | 168 | |
5 | Viruses Whose Life Cycle Uses Reverse Transcriptase | |
Family Retroviridae | 172 | |
Family Hepadnaviridae | 210 | |
6 | DNA-Containing Viruses | |
Family Poxviridae | 223 | |
Family Herpesviridae | 234 | |
Family Adenoviridae | 252 | |
Family Polyomaviridae | 259 | |
Family Papillomaviridae | 265 | |
Family Parvoviridae | 270 | |
TT Virus: A Newly Described Human Virus | 276 | |
7 | Subviral Agents | |
Defective Interfering Viruses | 279 | |
Satellites and Satellite Viruses | 283 | |
Viroids and Virusoids | 284 | |
Hepatitis [sigma] | 284 | |
Prions and Prion Diseases | 291 | |
8 | Host Defenses against Viral Infection and Viral Counterdefenses | |
Adaptive Immune System | 303 | |
Innate Immune System | 323 | |
Viral Counterdefenses | 334 | |
Interactions of Viruses with Their Hosts | 345 | |
9 | Gene Therapy | |
Virus Vector Systems | 347 | |
Use of Viruses as Expression Vectors | 357 | |
App. A: References for Figures | 367 | |
App. B: References for Tables | 373 | |
Index | 375 |
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