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List of illustrations | xiii | |
Acknowledgments | xv | |
1 | Methods of investigating brain function | 1 |
Introduction | 1 | |
Neuroanatomical techniques | 1 | |
Electron microscopy | 2 | |
Chemical staining | 3 | |
Brain scans | 4 | |
Neurophysiological techniques | 5 | |
Lesioning | 6 | |
Brain stimulation | 6 | |
Recording methods | 7 | |
Neurochemical methods | 8 | |
Chapter summary | 9 | |
2 | The neuron | 11 |
Introduction | 11 | |
The structure of the neuron | 11 | |
The neuronal membrane | 13 | |
The resting membrane potential | 13 | |
The action potential | 14 | |
Neurotransmitters | 16 | |
The synapse | 18 | |
Summation | 19 | |
Autoreceptors | 20 | |
Chapter summary | 20 | |
3 | Organisation of the central nervous system | 23 |
Introduction | 23 | |
Divisions of the mammalian nervous system | 24 | |
The spinal cord | 25 | |
The brain | 25 | |
Hindbrain | 28 | |
Midbrain | 28 | |
Forebrain | 30 | |
Functions of the CNS | 34 | |
Arousal | 35 | |
Emotion | 35 | |
Language | 35 | |
Chapter summary | 36 | |
4 | The autonomic nervous system | 39 |
Introduction | 39 | |
Structure of the ANS | 39 | |
Sympathetic and parasympathetic branches | 39 | |
Anatomy of the ANS | 40 | |
Central control of the ANS | 41 | |
Functions of the ANS | 42 | |
'Executive stress' and the formation of ulcers | 42 | |
Fight or flight | 44 | |
Chapter summary | 45 | |
5 | The endocrine system | 47 |
Introduction | 47 | |
Hormone release by the endocrine system | 48 | |
The hypothalamus and pituitary gland | 48 | |
Glandular hormones | 50 | |
Feedback mechanisms | 54 | |
Functions of the endocrine system | 56 | |
Endocrine reactions to stress | 56 | |
Endocrine control of the menstrual cycle | 57 | |
Other aspects of sexual behaviour | 57 | |
Chapter summary | 58 | |
6 | Homeostasis | 61 |
Introduction | 61 | |
What is homeostasis? | 62 | |
Temperature regulation | 63 | |
Control mechanisms of temperature regulation | 63 | |
Behavioural changes in anticipation of temperature requirements | 64 | |
Eating | 64 | |
Metabolism | 64 | |
Hunger | 65 | |
The glucostatic hypothesis | 66 | |
The lipostatic theory | 67 | |
The ischymetric hypothesis | 68 | |
Satiety | 68 | |
Summary of eating mechanisms | 70 | |
Drinking | 70 | |
Water compartments | 70 | |
Osmotic thirst | 72 | |
Volumetric thirst | 73 | |
Drinking satiety | 74 | |
Summary of drinking mechanisms | 75 | |
Chapter summary | 75 | |
7 | How drugs affect the brain | 79 |
Introduction | 79 | |
Types of effect that could occur | 80 | |
Possible sites for drug effects | 81 | |
Examples of drugs and their synaptic effects | 83 | |
Diazepam | 83 | |
Alcohol | 84 | |
Chapter summary | 84 | |
8 | Classifying psychoactive drugs | 87 |
Introduction | 87 | |
Sedative hypnotics | 88 | |
Stimulants | 89 | |
Opiate narcotics | 91 | |
Hallucinogens and psychedelics | 92 | |
Antipsychotic tranquillisers | 93 | |
Tolerance, dependence and withdrawal | 94 | |
Tolerance | 95 | |
Dependence and withdrawal | 95 | |
Chapter summary | 96 | |
9 | Drugs and behaviour | 99 |
Introduction | 99 | |
Depression and the antidepressants | 99 | |
Types of depression | 100 | |
Features of depression | 100 | |
The monoamine theory of depression | 101 | |
Drug treatments of depression | 101 | |
Schizophrenia and the antipsychotics | 103 | |
Features of schizophrenia | 103 | |
The dopamine hypothesis of schizophrenia | 104 | |
The serotonin link | 105 | |
Drug therapies of schizophrenia | 105 | |
The treatment of manic depression | 106 | |
Chapter summary | 106 | |
10 | Study aids | 109 |
Improving your essay writing skills | 109 | |
Practice essay 1 | 110 | |
Practice essay 2 | 112 | |
Practice essay 3 | 114 | |
Key research summary | 117 | |
Glossary | 119 | |
Bibliography | 131 | |
Index | 137 |
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