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Ch. 1 | Introduction to surrogate tissue analysis | 3 |
Ch. 2 | Impact of sample handling and preparation on gene signatures as exemplified for transcriptome analysis of peripheral blood | 15 |
Ch. 3 | Blood genomic fingerprints of brain diseases | 31 |
Ch. 4 | Transcriptional profiling of peripheral blood in oncology | 47 |
Ch. 5 | Blood-derived transcriptomic profiles as a means to monitor levels of toxicant exposure and the effects of toxicants on inaccessible target tissues | 65 |
Ch. 6 | Spermatozoal RNAs as surrogate markers of paternal exposure | 77 |
Ch. 7 | Proteomic analysis of surrogate tissues : mass spectrometry-based profiling of the circulatory proteome for cancer detection and stratification | 93 |
Ch. 8 | Lymphocyte integrins : potential surrogate biomarkers for evaluation of endometrial receptivity | 109 |
Ch. 9 | Nipple aspirate fluid to diagnose breast cancer and monitor response to treatment | 123 |
Ch. 10 | Metabonomics : metabolic profiling and pattern recognition analysis of body fluids and tissues for characterization of drug toxicity and disease diagnosis | 143 |
Ch. 11 | Comprehensive metabolomic profiling of serum and cerebrospinal fluid : understanding disease, human variability, and toxicity | 165 |
Ch. 12 | Lipidomic analysis of plasma and tissues : lipid-derived mediators of inflammation and markers of disease | 185 |
Ch. 13 | Molecular detection and characterization of circulating tumor cells and micrometastases in solid tumors | 203 |
Ch. 14 | Methylation profiling of tumor cells and tumor DNA in blood, urine, and body fluids for cancer detection and monitoring | 229 |
Ch. 15 | Regulatory and technical challenges in incorporating surrogate tissue profiling strategies into clinical development programs | 249 |
Ch. 16 | Considerations in the economic assessment of the value of molecular profiling | 263 |
Ch. 17 | The impact and challenges of pan-ornic approaches in pharmaceutical discovery and development | 275 |
Ch. 18 | Current and future aspects of surrogate tissue analysis | 291 |
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Add Surrogate Tissue Analysis: Genomic, Proteomic, and Metabolomic Approaches, Despite rapidly expanding interest in potential applications of surrogate tissue analysis and intense competition to identify and validate biomarkers in appropriate surrogate tissues, very few peer reviewed publications describing the use of this approach, Surrogate Tissue Analysis: Genomic, Proteomic, and Metabolomic Approaches to the inventory that you are selling on WonderClubX
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Add Surrogate Tissue Analysis: Genomic, Proteomic, and Metabolomic Approaches, Despite rapidly expanding interest in potential applications of surrogate tissue analysis and intense competition to identify and validate biomarkers in appropriate surrogate tissues, very few peer reviewed publications describing the use of this approach, Surrogate Tissue Analysis: Genomic, Proteomic, and Metabolomic Approaches to your collection on WonderClub |