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Preface
1 Background 1
About Teamwork 1
Sources of Error and Epidemiologic Thinking 3
Interpreting the Relative Value of Studies 10
The HIV/AIDS Epidemic Today 16
2 Causes and Sources of AIDS 21
Cytomegalovirus 21
Human T-Cell Lymphotropic Virus Type III (HTLV-III) 23
HIV-2, HTLV-IV (and...SIV and STLV...) 27
Does HIV-2 Protect against HIV-1? 29
"Poppers" and Kaposi's Sarcoma 31
African Swine Fever Virus 33
HIV Does Not Cause AIDS 35
The Source of HIV and AIDS 36
The River 38
Other Theories 40
3 Counting Cases 47
What Is the Future of AIDS? Modeling the Past to Estimate the Future 53
Estimating the Impact of AIDS 54
Idiopathic CD4-Lymphocytopenia (ICL), or the "AIDS, Not!" Syndrome 62
HIV Reporting 64
4 Epidemiologic Controversies 75
Issues in Sexual Transmission 77
Blood and Blood Products 81
"Silent Sequences" 85
A Florida Dentist 88
"Safe" Insemination 90
5 Unusual and Unproven Modes of HIV Transmission 99
"No Identified Risk" 100
Health Care Workers 102
The Environment 103
Insects 105
Belle Glade 107
Saliva and Biting 109
Food 111
Sweat, Tears, and Urine 112
Household Transmission 113
6 Issues in Prevention 121
HIV Testing 122
The Person at Risk, or the Person Known to Be HIV-Infected? 128
Preventing Mother-to-Infant Spread 131
Needle and Syringe Exchange; Condom Provision 133
Circumcision 136
7 Early Drugs and Biomedical Interventions 147
The "Pre-Zidovudine" Drugs 147
Experimental Antiretroviral Therapies Now Largely Abandoned 154
Zidovudine 156
After Zidovudine 160
8 The Modern Therapeutic Era (after 1995) 171
When to Start Therapy in HIV-Infected People without Symptoms173
Lipodystrophy 179
Protease Inhibitors and Cardiovascular Disease 182
Early Vaccines and Microbicides 184
Strategic Treatment Interruptions 185
9 Errors, Their Consequences, and Their Management 199
Types of Errors and Their Consequences 200
Human Bias 205
Bureaucracy, the "Killer Bees," and Other Considerations about Retarding Research 208
Journals 213
Higher Education 215
Appendix Antiretroviral Drugs Approved by the U.S. Food and Drug Administration, 2007 221
Index 223
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Lucas Duebendorfer
reviewed Scientific Errors and Controversies in the U.S. HIV/Aids Epidemic: How They Slowed Advances and Were Resolved on September 20, 2010
Scientific Errors and Controversies in the U.S. HIV/Aids Epidemic
Hmm. Judging by the high ratings, some people were surprised to hear that the harder you work at stuff, the better you get. The surprise is that this is a surprise to some people.
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Add Scientific Errors and Controversies in the U.S. HIV/Aids Epidemic: How They Slowed Advances and Were Resolved, Our understanding, prevention, and treatment of HIV have made remarkable strides in the past two decades, but the way has not been smooth or straight. Part history, part narrative, and mainly scientific autopsy, this book is an insider's account of the er, Scientific Errors and Controversies in the U.S. HIV/Aids Epidemic: How They Slowed Advances and Were Resolved to the inventory that you are selling on WonderClubX
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