Risk markers for oral diseases Book

1. Introduction: current concepts of the nature and natural history of periodontal diseases and the need for disease markers; Part I. Evidence for the Existence of High Risk Groups and Individuals: 2. The distribution of periodontal destruction in the populations of industrialized countries; 3. The distribution of periodontal destruction in the populations of non-industrialized countries: evidence for the existence of high risk groups and individuals; 4. Severe forms of periodontitis in children, juveniles and adults: worldwide prevalence; Part II. Methods for the Characterization of High Risk Groups and Individuals: 5. Unchanging, subject-based risk factors for destructive periodontitis: race, sex, genetic, congenital and childhood systemic diseases; 6. Changing subject-based risk factors for destructive periodontitis; 7. Clinical markers of active periodontal disease; 8. Immunological procedures for diagnosis and risk assessment in periodontal diseases; 9. Markers of periodontal disease susceptibility and activity derived from saliva; 10. Markers of periodontal disease susceptibility and activity derived from gingival crevicular fluid: specific vs. non-specific analyses; 11. Host-derived enzyme activities in gingival crevicular fluid as markers of periodontal disease susceptibility and activity: historical perspective, biological significance and clinical implications; 12. Prostaglandins and other eicanosoids in gingival crevicular fluid as markers of periodontal disease activity; 13. The connective tissues of the periodontium and their breakdown products in gingival crevicular fluid as markers of periodontal disease activity; 14. Do bacterial markers exist in subgingival plaque for predicting periodontal disease susceptibility?; 15. New methods for microbial screening in the diagnosis of periodontal infections: cultural, immunological, gene probes; Part III. Practical Applications and Implications: 16. Microbiologically based diagnostic tests for periodontitis. Considerations of sensitivity, specificity and accuracy; 17. The implications of the high risk strategy and of improved diagnostic methods for health screening and public health planning in periodontal diseases.