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Polymeric Gene Delivery: Principles and Applications Book

Polymeric Gene Delivery: Principles and Applications
Polymeric Gene Delivery: Principles and Applications, To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popul, Polymeric Gene Delivery: Principles and Applications has a rating of 3 stars
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Polymeric Gene Delivery: Principles and Applications, To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popul, Polymeric Gene Delivery: Principles and Applications
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  • Polymeric Gene Delivery: Principles and Applications
  • Written by author Mansoor M. Amiji
  • Published by Taylor & Francis, Inc., September 2004
  • To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popul
  • To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popul
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Ch. 1Introduction1
Ch. 2Tissue- and cell-specific targeting for the delivery of genetic information5
Ch. 3Biological barriers to gene transfer29
Ch. 4Cellular uptake and trafficking43
Ch. 5Pharmacokinetics of polymer-plasmid DNA complex63
Ch. 6Poly(L-lysine) and copolymers for gene delivery79
Ch. 7Gene delivery using polyethylenimine and copolymers97
Ch. 8Poly(2-(dimethylamino)ethyl methacrylate)-based polymers for the delivery of genes in vitro and in vivo107
Ch. 9Cationic dendrimers as gene transfection vectors : dendri-poly(amidoamines) and dendri-poly(propylenimines)133
Ch. 10Poly(ethylene glycol)-conjugated cationic dendrimers159
Ch. 11Water-soluble lipopolymers for gene delivery175
Ch. 12Cyclodextrin-containing polymers for gene delivery187
Ch. 13Gene delivery using polyimidazoles and related polymers213
Ch. 14Degradable poly([beta]-amino ester)s for gene delivery227
Ch. 15Cationic polyesters as biodegradable polymeric gene delivery carriers243
Ch. 16Poly(amidoamine)s for gene delivery255
Ch. 17Cationic polysaccharides for gene delivery279
Ch. 18Gene delivery using chitosan and chitosan derivatives301
Ch. 19Pluronic block copolymers for nonviral gene delivery313
Ch. 20Use of poly(N-vinyl pyrrolidone) with noncondensed plasmid DNA formulations for gene therapy and vaccines329
Ch. 21Use of HPMA copolymers in gene delivery345
Ch. 22Biodegradable nanoparticles as a gene expression vector357
Ch. 23Nanoparticles made of poly(lactic acid) and poly(ethylene oxide) as carriers of plasmid DNA367
Ch. 24Poly(alkylcyanoacrylate) nanoparticles for nucleic acid delivery387
Ch. 25Layer-by-layer nanoengineering with polyelectrolytes for delivery of bioactive materials399
Ch. 26Ex vivo and in vivo adenovirus-mediated gene delivery into refractory cells via nanoparticle hydrogel formulation417
Ch. 27Protein nanoparticles for gene delivery429
Ch. 28Gene delivery using poly(lactide-co-glycolide) microspheres451
Ch. 29Polyanhydride microspheres for gene delivery467
Ch. 30Microspheres formulated from native hyaluronan for applications in gene therapy475
Ch. 31Genetically engineered protein-based polymers : potential in gene delivery489
Ch. 32Glycopolymer tools for studying targeted nonviral gene delivery509
Ch. 33Targeted gene delivery via the folate receptor523
Ch. 34Transferrin receptor-targeted gene delivery systems537
Ch. 35Gene delivery to the lungs557
Ch. 36Cutaneous gene delivery573
Ch. 37Enhancement of wound repair by sustained gene transfer via hyaluronan matrices589
Ch. 38Gene delivery from tissue engineering matrices611
Ch. 39Gene therapy stents for in-stent restenosis625
Ch. 40Gene delivery using BioMEMS659


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