Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research Book

Part I. Polyamines in Signal Transduction of Cell Proliferation

Polyamine Structure and Synthetic Analogs

Patrick M. Woster

Acute Increases in Intracellular Putrescine Lead to the Increase in Steady-State Levels of c-fos, c-jun, RING3, and Id-1 mRNAs

Allan A. Ancheta, Leo Hawel, III, and Craig V. Byus

Polyamine-Dependent Early Cellular Signals and Cell Proliferation

Stina M. Oredsson

Cellular Signals Mediating Growth Arrest After Polyamine Depletion

Jian-Ying Wang

Role of Polyamines in the Regulation of Chromatin Acetylation

Cheryl A. Hobbs and Susan K. Gilmour

Role of Polyamines in Regulation of Sequence-Specific DNA Binding Activity

Sripriya Venkiteswaran, Thresia Thomas, and T. J. Thomas

Polyamine Metabolism and the Hypertrophic Heart

Lisa M. Shantz and Emanuele Giordano

Influence of Polyamines on Breast Cancer Biology

Andrea Manni

Polyamines in Regulation of Prostatic Cell Growth

Raymond G. Schipper, Vincent Cuijpers, Johannes C. Romijn, and Albert A. J. Verhofstad

Polyamines in Kidney Biology

Joseph Satriano

Polyamines in Pulmonary Vascular Biology

Jack W. Olson and Mark N. Gillespie

Part II. Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy

Recent Advances in the Understanding of Mammalian Polyamine Catabolism: The Regulation and Potential Role of Polyamine Catabolism in Drug Response and Disease Processes

Robert A. Casero, Jr., Alison V. Fraser, Tracy Murray-Stewart, Amy Hacker, Naveen Babbar, Jennifer Fleischer, and Yanlin Wang

Cellular Signaling and Polyamines in the Control of Apoptosis in Intestinal Epithelial Cells

Leonard R. Johnson and Ramesh M. Ray

The Role of Ornithine Decarboxylase in Myc-Induced Tumorigenesis

Jonas A. Nilsson and John L. Cleveland

Protective Effect of Polyamines on NSAID-Induced Injury and Apoptosis

Heather M. Wallace and Alun Hughes

Role of Polyamines in the Control of the Immune Response in the Brain

Denis Soulet and Serge Rivest

Implication of Polyamines in Apoptosis of Immunoresponse Cells

Rupesh Chaturvedi and Keith T. Wilson

Polyamines and Cancer

Ajit K. Verma

Polyamine Pools and Cancer Prevention

Eugene W. Gerner and David E. Stringer

Part III. Polyamines in Cell Motility and Cell-Cell Interactions

Polyamines and Cytoskeletal Regulation During Intestinal Epithelial Restitution

Ramesh M. Ray and Leonard R. Johnson

Regulation of Kv Channel Activity and Intercellular Junctions by Polyamines in Intestinal Epithelial Cells

Jaladanki N. Rao and Jian-Ying Wang

Polyamine Block of Kir Channels: Toward a Molecular Picture

Harley T. Kurata and Colin G. Nichols

Part IV. Polyamine Homeostasis and Transport

Regulation of Ornithine Decarboxylase Expression

Lo Persson

Evidence for a Multistep Model for Eukaryotic Polyamine Transport

Richard Poulin, Denis Soulet, Bruno Gagnon, Serge Rivest, and Marie Audette

Bacterial and Eukaryotic Transport Systems

Kazuei Igarashi and Keiko Kashiwagi

Regulation of S-Adenosylmethionine Decarboxylase

Colin Hanfrey

Genetic Engineering of Polyamine Catabolism in Transgenic Mice and Rats

Juhani Jänne, Leena Alhonen, Marko Pietilä, Tuomo A. Keinänen, Suvikki Suppola, Eija Pirinen, Mervi T. Hyvönen, Aki Järvinen, and Markku Laakso

Index