Nucleic Acid Targeted Drug Design Book

"Designing Drugs that Interact with Nucleic Acids, Thomas J. Perun and C. L. Propst Methods Structural Studies of Drug-DNA Interactions by X-ray Crystallography and NMR Spectroscopy, Andrew H. -J. Wang and Howard Robinson Modeling Drug-Nucleic Acid Interactions: An Exercise in Computer Graphics and Computational Chemistry, Shashidhar N. Rao Sequence Specificity of Drug-DNA Interactions, James C. Dabrowiak, Allison A. Stankus, and Jerry Goodisman Construction of Quantitative Structure-Activity Relationships (QSARs) from Ligand-DNA Molecular Modeling Studies, A. J. Hopfinger, Mario Gustavo Cardozo, and Yoshiyuki Kawakami The Molecular Basis of Sequence-Specific DNA-Protein Interactions, Thomas Kodadek Applications Netropsin and the Lexitropsins: The Search for Sequence-Specific Minor-Groove-Binding Ligands, Mary L. Kopka and Teresa A. Larsen Pyrrolo (1,4) benzodiazepines: Unraveling the Complexity of the Structures of the Tomaymycin-DNA Adducts in Various Sequences Using Fluorescence, 1H-NMR, and Molecular Modeling, William A. Remers, Mary D. Barkley, and Laurence H. Hurley A Cooperative Quinolone-DNA Binding Model for DNA Gyrase Inhibition: Implications in Drug Design, Lester A. Mitscher and Linus L. Shen Mechanism of DNA Damage by Neocarzinostatin and Other Bicyclic Enediyne Antibiotics, Peter C. Dedon and Irving H. Goldberg Comparative Studies of Intercalative DNA-Drug Interactions Using Molecular Modeling and Biophysical Techniques, Mavis Agbandje and Robert McKenna Catalytic Antisense RNAs: Principles and Design, James O. Deshler and John J. Rossi Oligonucleiotide-Based Therapeutics, Norbert Bischofberger and Regan G. Shea "