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Molecular Basis of Aging Book

Molecular Basis of Aging
Molecular Basis of Aging, Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach pr, Molecular Basis of Aging has a rating of 3 stars
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Molecular Basis of Aging, Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach pr, Molecular Basis of Aging
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  • Molecular Basis of Aging
  • Written by author Alvaro Macieira-Coelho
  • Published by CRC Press, July 1995
  • Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach pr
  • Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach pr
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Introduction1
Ch. 1Reorganization of the Genome during Aging of Proliferative Cell Compartments21
Ch. 2Genomic Instability during Aging of Postmitotic Mammalian Cells71
Ch. 3DNA Repair during Aging137
Ch. 4Changes in Gene Expression during Aging of Mammals183
Ch. 5Role of Mitochondria in Cell Aging219
Ch. 6Modifications of the Cell Surface Leading to Cell Elimination237
Ch. 7Protein Kinase C Signal Transmission during Aging269
Ch. 8Changes in Transmembrane Signaling Mechanisms during Aging: Cellular and Molecular Aspects293
Ch. 9Structural Changes Modifying the Intracellular Flow of Information307
Ch. 10The Aging of the Neuronal Cytoskeleton327
Ch. 11Transport of mRNA into the Cytoplasm353
Ch. 12Translational and Post-translational Modifications during Aging389
Ch. 13Carbonyl Toxification Hypothesis of Biological Aging421
Ch. 14Amyloidosis and Aging437
Ch. 15Extracellular Matrix459
Ch. 16Brain Metabolism during Aging493
Ch. 17Central Neurotransmission in the Elderly511
Ch. 18Age-Related Changes in Neuropeptidergic Neurons in the Human Hypothalamus527
Index533


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