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Microtubule Targets in Cancer Therapy Book

Microtubule Targets in Cancer Therapy
Microtubule Targets in Cancer Therapy, This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest, Microtubule Targets in Cancer Therapy has a rating of 3 stars
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Microtubule Targets in Cancer Therapy, This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest, Microtubule Targets in Cancer Therapy
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  • Microtubule Targets in Cancer Therapy
  • Written by author Tito Fojo
  • Published by Springer-Verlag New York, LLC, July 2008
  • This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest
  • The family of proteins called the tubulin and the microtubules they form when they aggregate are extremely important in the cell and, as we are increasingly learning, important in diseases that afflict so many. This field of investigation is a testament t
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Authors

Preface     vii
Contributors     xi
List of Color Plates     xiii
An Overview of Compounds That Interact with Tubulin and Their Effects on Microtubule Assembly   Ernest Hamel     1
Molecular Mechanisms of Microtubule Acting Cancer Drugs   John J. Correia   Sharon Lobert     21
Microtubule Dynamics: Mechanisms and Regulation by Microtubule-Associated Proteins and Drugs In Vitro and in Cells   Mary Ann Jordan   Leslie Wilson     47
Microtubule Associated Proteins and Microtubule-Interacting Proteins: Regulators of Microtubule Dynamics   Maria Kavallaris   Sima Don   Nicole M. Verrills     83
The Post-Translational Modifications of Tubulin   Richard F. Luduena   Asok Banerjee     105
The Isotypes of Tubulin: Distribution and Functional Significance   Richard F. Luduena   Asok Banerjee     123
The Tubulin Superfamily   Richard F. Luduena   Asok Banerjee     177
Tubulin Proteomics in Cancer   Pascal Verdier-Pinard   Fang Wang   Ruth Hogue Angeletti   Susan Band Horwitz   George A. Orr     193
Tubulin and Microtubule Structures   Eva Nogales   Kenneth H. Downing     211
Destabilizing Agents: Peptides and Depsipeptides   Lee M. Greenberger   Frank Loganzo     227
Molecular Features of the Interaction of Colchicine and Related Structures with Tubulin   Susan L. Bane     259
Antimicrotubule Agents That Bind Covalently to Tubulin   Dan L. Sackett     281
Microtubule Stabilizing Agents   Susan Band Horwitz   Tito Fojo     307
Mechanisms of Resistance to Drugs That Interfere with Microtubule Assembly   Fernando Cabral     337
Resistance to Microtubule-Targeting Drugs   Paraskevi Giannakakou   James P. Snyder     357
Microtubule Stabilizing Agents in Clinical Oncology: The Taxanes   Chris H. Takimoto   Muralidhar Beeram     395
Investigational Anticancer Agents Targeting the Microtubule   Lyudmila A. Vereshchagina   Orit Scharf   A. Dimitrios Colevas     421
Microtubule Damaging Agents and Apoptosis   Manon Carre   Diane Braguer     479
Microtubule Targeting Agents and the Tumor Vasculature   Raffaella Giavazzi   Katiuscia Bonezzi   Giulia Taraboletti     519
Neurodegenerative Diseases: Tau Proteins in Neurodegenerative Diseases Other Than AD   Andre Delacourte    Nicolas Sergeant   Luc Buee     531
Structure, Function, and Regulation of the Microtubule Associated Protein Tau   Janis Bunker   Stuart C. Feinstein     559
Index     577


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Microtubule Targets in Cancer Therapy, This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest, Microtubule Targets in Cancer Therapy

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Microtubule Targets in Cancer Therapy, This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest, Microtubule Targets in Cancer Therapy

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Microtubule Targets in Cancer Therapy, This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and invest, Microtubule Targets in Cancer Therapy

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