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Medical Uses of Statistics Book

Medical Uses of Statistics
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Medical Uses of Statistics, Medical Uses of Statistics has served as one of the most influential works on the subject for physicians, physicians-in-training, and a myriad of healthcare experts who need a clear idea of the proper application of statistical techniques in clinical stud, Medical Uses of Statistics
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  • Medical Uses of Statistics
  • Written by author John C. Bailar
  • Published by Wiley, John & Sons, Incorporated, 1/10/2012
  • Medical Uses of Statistics has served as one of the most influential works on the subject for physicians, physicians-in-training, and a myriad of healthcare experts who need a clear idea of the proper application of statistical techniques in clinical stud
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Authors

Contributors xi

Preface xv

Preface to the Second Edition xvii

Preface to the First Edition xviii

Acknowledgments xxi

Origins of Chapters xxiii

Introduction xxv

Section I Broad Concepts and Analytic Techniques

Chapter 1 Statistical Concepts Fundamental to Investigations Lincoln E. Moses 1

Chapter 2 Some Uses of Statistical Thinking John C. Bailar 21

Chapter 3 Use of Statistical Analysis in the New England Journal of Medicine Shilpi Agarwal Graham A. Colditz John D. Emerson 41

Section II Design

Chapter 4 Randomized Trials and Other Parallel Comparisons of Treatment Nancy E. Mayo 51

Chapter 5 Crossover and Self-Controlled Designs in Clinical Research John C. Bailar Thomas A. Louis Philip W. Lavori Marcia Polansky 91

Chapter 6 The Series of Consecutive Cases as a Device for Assessing Outcomes of Interventions Lincoln E. Moses 109

Chapter 7 Biostatistics in Epidemiology: Design and Basic Analysis Mark S. Goldberg 123

Section III Analysis

Chapter 8 p-Values James H. Ware Frederick Mosteller Fernando Delgado Christl Donnelly Joseph A. Ingelfinger 175

Chapter 9 Understanding Analyses of Randomized Trials Nancy E. Mayo 195

Chapter 10 Linear Regression in Medical Research Paul J. Rathouz Amita Rastogi 239

Chapter 11 Statistical Analysis of Survival Data Stephen W. Lagakos 277

Chapter 12 Analysis of Categorical Data in Medical Studies Paul S. Albert 291

Chapter 13 Analyzing Data from Ordered Categories Lincoln E. Moses John D. Emerson Hossein Hosseini 311

Section IV Communicating Results

Chapter 14 Guidelines for Statistical Reporting in Articles for Medical Journals: Amplifications and Explanations John C. Bailar Frederick Mosteller325

Chapter 15 Reporting of Subgroup Analyses in Clinical Trials Rui Wang Stephen W. Lagakos James H. Ware David J. Hunter Jeffrey M. Drazen 343

Chapter 16 Writing about Numbers Frederick Mosteller Margaret Perkins Stephen Morrissey 353

Section V Specialized Methods

Chapter 17 Combining Results from Independent Studies: Systematic Reviews and Meta-Analysis in Clinical Research Michael A. Stoto 369

Chapter 18 Biostatistics in Epidemiology: Advanced Methods of Regression Analysis Mark S. Goldberg 399

Chapter 19 Genetic Inference Dan L. Nicolae Thorsten Kurz Carole Ober 439

Chapter 20 Identifying Disease Genes in Association Studies Dan L. Nicolae Thorsten Kurz Carole Ober 455

Chapter 21 Risk Assessment A. John Bailer John C. Bailar 467

Index 483


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