Mammalian proteases Book

This volume on exopeptidases and its forerunner, Volume 1, on endopeptidases are designed to serve as the primary reference work in the field. They summarize the identifying properties, physico-chemical characteristics, and supporting publications for the proteases (proteinases and peptidases) that constitute the pathways of intracellular and extracellular protein breakdown in mammalian cells and tissues. The exopeptidases described here include a wide range of peptide hydrolases whose highly varied speficities make important contributions to the metabolism of peptides and proteins. Knowledge of the proteases has now gone far beyond the stage at which the individual scientists can expect to have read most of the relevant original papers, yet many reviews of the literature are inadequate to the needs of researchers. As a possible remedy, this book represents a computer-aided system for the codification of current data. It provides a concise, easily accessible, summary of properties for each enzyme, together with a comprehensive bibliography arranged chronologically and alphabetically.