Helicobacter Pylori: Physiology and Genetics Book

	Contributors
	Preface
	Acknowledgments
1	Overview	3
2	Epidemiology of Infection	7
3	One Hundred Years of Discovery and Rediscovery of Helicobacter pylori and Its Association with Peptic Ulcer Disease	19
4	Basic Bacteriology and Culture	27
5	Taxonomy of the Helicobacter Genus	39
6	Morphology and Ultrastructure	53
7	Cell Envelope	69
8	Molecular Structure, Biosynthesis, and Pathogenic Roles of Lipopolysaccharides	81
9	Vacuolating Cytotoxin	97
10	Microaerobic Physiology: Aerobic Respiration, Anaerobic Respiration, and Carbon Dioxide Metabolism	113
11	Nitrogen Metabolism	125
12	The Citric Acid Cycle and Fatty Acid Biosynthesis	135
13	Nucleotide Metabolism	147
14	Biosynthetic Pathways Related to Cell Structure and Function	159
15	Evasion of the Toxic Effects of Oxygen	167
16	Urease	179
17	Ion Metabolism and Transport	193
18	Metabolite Transport	207
19	Protein Export	219
20	Alternative Mechanisms of Protein Release	227
21	Motility, Chemotaxis, and Flagella	239
22	Natural Transformation, Recombination, and Repair	249
23	Chromosomal Replication, Plasmid Replication, and Cell Division	259
24	Restriction and Modification Systems	269
25	Regulation of Urease for Acid Habitation	277
26	Transcription and Translation	285
27	The Genome	295
28	Genetic Exchange	313
29	Gene Regulation	321
30	Mutagenesis	335
31	The cag Pathogenicity Island	345
32	Population Genetics	355
33	Heterogeneity and Subtyping	363
34	Adherence Colonization	381
35	Lipopolysaccharide Lewis Antigens	419
36	Gastric Autoimmunity	429
37	Vaccines	441
38	Pathology of Gastritis and Peptic Ulceration	459
39	Host Inflammatory Response to Infection	471
40	Gastric Cancer	481
41	Markers of Infection	499
42	Antibiotic Susceptibility and Resistance	511
43	Enterohepatic Helicobacter Species	533
44	Other Gastric Helicobacters and Spiral Organisms	549
45	In Vivo Modeling of Helicobacter-Associated Gastrointestinal Diseases	565
46	In Vivo Adaptation to the Host	583
	Index	593