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Handbook of Toxicologic Pathology,Two-Volume Set Book

Handbook of Toxicologic Pathology,Two-Volume Set
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  • Handbook of Toxicologic Pathology,Two-Volume Set
  • Written by author Wanda M. Haschek
  • Published by Elsevier Science, October 2001
  • A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic Pathology relies heavily on the fields of both to
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Volume 1: General Toxicologic Pathology

Preface.
Contributors.

Part A: Basics of Toxicologic Pathology
Toxicologic Pathology: An Introduction.
Biochemical Basis of Toxicity.
Morphologic Manifestation of Toxic Cell Injury.
Organelle Biochemistry and Regulation of Cell Death.
Carcinogenesis.
Applied Clinical Pathology in Preclinical Toxicology Testing.
Nomenclature.

Part B: The Practice of Toxicologic Pathology
Basic Techniques.
Managing Pitfalls in Toxicologic Pathology.
Special Techniques in Toxicologic Pathology.
Application of New Technologies to Toxicologic Pathology.
Issues in Laboratory Animal Science for the Toxicologic Pathologist.
New Animal Models in Toxicology.
Pathology Issues in the Design of Toxicology Studies.
Use and Misuse of Statistics in the Design and Interpretation of Studies.
Preparation of the Report for a Toxicology/Pathology Study.

Part C: Selected Topics in Toxicologic Pathology
Risk Assessment: The Changing Paradigm.
Principles of Risk Communication: Building Trust and Credibility with the Public.
Biomedical Devices and Biomaterials.
Biotechnology and Its Products.
Endocrine Disruptors.
Radiation and Heat.
Nutritional Toxicologic Pathology.
Phycotoxins.
Mycotoxins.
Heavy Metals.

Volume 2: Organ Specific Toxicologic Pathology

Organ-Specific Toxicologic Pathology: An Introduction.
Respiratory System.
Skin and Oral Mucosa.
Gastrointestinal Tract.
Liver.
Pancreas.
Kidney.
Lower Urinary Tract.
Cardiovascular and Skeletal Muscle Systems.
Bones and Joints.
Nervous System.
The Eye.
Immune System.
Hematopoietic System.
Endocrine System.
Male Reproduction.
Female Reproduction.
Embryo and Fetus.

Index.


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