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Handbook of Chiral Chemicals Book

Handbook of Chiral Chemicals
Handbook of Chiral Chemicals, As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. The Handbook of Chiral Chemicals, Second Edition highlights the, Handbook of Chiral Chemicals has a rating of 3 stars
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Handbook of Chiral Chemicals, As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. The Handbook of Chiral Chemicals, Second Edition highlights the, Handbook of Chiral Chemicals
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  • Handbook of Chiral Chemicals
  • Written by author David Ager
  • Published by Taylor & Francis, Inc., October 2005
  • As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. The Handbook of Chiral Chemicals, Second Edition highlights the
  • In the context of the move by pharmaceutical companies to develop single enantiomers as drug candidates, researchers from companies and a few universities in Europe, North America, and Australia highlight the problems associated with producing chiral comp
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Book Categories

Authors

Ch. 1Introduction1
Ch. 2Amino acids11
Ch. 3Microbial pathway engineering for amino acid manufacture31
Ch. 4Carbohydrates in synthesis47
Ch. 5Terpenes : the expansion of the chiral pool59
Ch. 6Resolutions at large scale : case studies75
Ch. 7New developments in crystallization-induced resolution97
Ch. 8The role of cis-1-amino-2-indanol in resolution processes117
Ch. 9Asymmetric oxidations123
Ch. 10Asymmetric epoxidation of olefins by chiral ketones147
Ch. 11Ozonolysis in the production of chiral fine chemicals165
Ch. 12Transition metal catalyzed hydrogenations, isomerizations, and other reactions185
Ch. 13Modular, chiral P-heterocycles in asymmetric catalysis249
Ch. 14Asymmetric olefin hydrogenation using monodentate BINOL- and bisphenol-based ligands : phosphonites, phosphites, and phosphoramidites269
Ch. 15Asymmetric catalytic hydrogenation reactions with ferrocene-based diphosphine ligands287
Ch. 16Asymmetric reduction of prochiral ketones catalyzed by oxazaborolidines305
Ch. 17cis-1-amino-2-indanol-derived ligands in asymmetric catalysis319
Ch. 18Enantioselective hydrogenation of activated ketones using heterogeneous Pt catalysts modified with cinchona alkaloids345
Ch. 19Biotransformations : "green" processes for the synthesis of chiral fine chemicals359
Ch. 20Combining enzyme discovery and evolution to develop biocatalysts405
Ch. 21One-pot synthesis and the integration of chemical and biocatalytic conversions419
Ch. 22Substitution reactions429
Ch. 23Industrial applications of chiral auxiliaries443
Ch. 24The role and importance of cis-1-amino-2-indanol in biological systems and asymmetric processes457
Ch. 25Enantiopure amines by chirality transfer using (R)-phenylglycine amide487
Ch. 26Pericyclic reactions503
Ch. 27Asymmetric free-radical reductions mediated by chiral stannanes, germanes, and silanes531
Ch. 28Metathesis reactions539
Ch. 29Synthesis of homochiral compounds : a small company's role559
Ch. 30Commercial synthesis of the antiglaucoma prostanoid travoprost573
Ch. 31Synthesis of large volume products589


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