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Hardbound. This volume contains presentations of the 16th Yokohama 21st Century Forum on Brain Sciences in the Coming Century, entitled Frontiers of the Mechanisms of Memory and Dementia held in Japan in November 1999. The symposium included 19 invited speakers and 53 poster presentations. Over 150 scientists from around the world attended the meeting.Main features of this monograph cover the molecular mechanisms of long-term potentiation, the mechanisms of cell death and apoptosis and the recent research on memory and dementia. Multiple mechanisms have been proposed to mediate memory and learning encompassing molecular, neurochemical, neuronal, synaptic, network, neural systems and behavioral processes. The purpose of this volume is to review the state of knowledge in the topics of memory, cell death, neuroprotection, animal models of memory impairment, neuropathology and neuroimaging of dementing illness and
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