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From Basic Immunology to Immune-Mediated Demyelination Book

From Basic Immunology to Immune-Mediated Demyelination
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From Basic Immunology to Immune-Mediated Demyelination, This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, From Basic Immunology to Immune-Mediated Demyelination
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  • From Basic Immunology to Immune-Mediated Demyelination
  • Written by author Gianvito Martino
  • Published by Springer-Verlag New York, LLC, 1/28/2013
  • This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology
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Ch. 1 Protective Versus Harmful Responses and Immune Regulation 1
Ch. 2 Antigen Recognition and Autoimmunity 7
Ch. 3 Assembly and Function of Immunoglobulins During B Cell Development 16
Ch. 4 Pathogenetic Mechanisms of Autoimmunity 26
Ch. 5 Adhesion Receptors Involved in Leukocyte Functions 38
Ch. 6 The Endothelium of the Brain Microvasculature and the Organization of Intercellular Junctions 47
Ch. 7 Chemokines and Chemokine Receptors 58
Ch. 8 Th1/Th2 Cytokine Network 68
Ch. 9 Lymphocyte Trafficking in the Central Nervous System 83
Ch. 10 Antigen Presentation in the Central Nervous System 89
Ch. 11 Myelination of the Central Nervous System 101
Ch. 12 Genomic Screening in Multiple Sclerosis 116
Ch. 13 MHC and Multiple Sclerosis 130
Ch. 14 Cytokine Genes in Multiple Sclerosis 137
Ch. 15 Adhesion Molecules and the and Blood-Brain-Barrier in Multiple Sclerosis 149
Ch. 16 Non-Myelin Antigen Autoreactivity in Multiple Sclerosis 162
Ch. 17 Myelin Antigen Autoreactivity in Multiple Sclerosis 170
Ch. 18 Inflammation and Multiple Sclerosis: a Close Interplay 185
Ch. 19 Magnetic Resonance and Blood-Brain Barrier Dysfunction in Multiple Sclerosis 195
Ch. 20 Immunotherapies for Multiple Sclerosis 210
Ch. 21 Animal Models of Demyelination of the Central Nervous System 233
Ch. 22 MHC and Non-MHC Genetics of Experimental Autoimmune Encephalomyelitis 246
Ch. 23 Genetics of Hereditary Neuropathies 265
Ch. 24 Immunopathogenetic Role of Anti-Neural Antibodies in Demyelinating Dysimmune Neuropathies 274
Ch. 25 Treatment of Inflammatory Demyelinating Polyneuropathy 287
Subject Index 313


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From Basic Immunology to Immune-Mediated Demyelination, This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, From Basic Immunology to Immune-Mediated Demyelination

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From Basic Immunology to Immune-Mediated Demyelination, This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, From Basic Immunology to Immune-Mediated Demyelination

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From Basic Immunology to Immune-Mediated Demyelination, This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, From Basic Immunology to Immune-Mediated Demyelination

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