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Book Categories |
List of contributors | ||
Foreword | ||
Preface | ||
1 | Introduction | 3 |
2 | Overview of the clinical genetics of breast cancer | 6 |
3 | Cowden syndrome and related disorders | 22 |
4 | Overview of the clinical genetics of ovarian cancer | 43 |
5 | Ovarian and breast cancer as part of hereditary non-polyposis colorectal cancer (HNPCC) and other hereditary colorectal cancer syndromes | 73 |
6 | The natural history of hereditary breast cancer | 81 |
7 | Pathology of the breast and ovary in mutation carriers | 108 |
8 | Risk estimation for familial breast and ovarian cancer | 125 |
9 | Developing a cancer genetics service: a Welsh model | 143 |
10 | Referral criteria for cancer genetics clinics | 157 |
11 | Guidelines for the development of cancer genetics services | 166 |
12 | Cultural and educational aspects influencing the development of cancer genetics services in different European countries | 194 |
13 | Screening, detection and survival patterns of breast and other cancers in high-risk families | 204 |
14 | Screening for familial ovarian cancer | 220 |
15 | Management of BRCA1/2 mutation carriers | 237 |
16 | Management of familial ovarian cancer | 275 |
17 | Prophylactic mastectomy in mutation carriers | 286 |
18 | Psychosocial aspects of genetic counselling for breast and ovarian cancer | 295 |
19 | BRCA1/2 testing: uptake and its measurement | 306 |
20 | Breast cancer genetics: ethical, social and insurance issues | 339 |
21 | Gene therapy for breast and ovarian cancer | 372 |
22 | Future directions | 384 |
Index | 393 |
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