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Preface | ||
Chapter 1 | Clinical Pharmacology of SERMs and Pure Anti-estrogens | 1 |
Chapter 2 | Aromatase Inhibitors: The Third Generation | 17 |
Chapter 3 | Systemic Therapy of Metastatic Breast Cancer in Postmenopausal Patients | 13 |
Chapter 4 | ATAC: Early Breast Cancer | 47 |
Chapter 5 | Aromatase Inhibitors and Other Agents in Early-Stage Breast Cancer | 55 |
Chapter 6 | Neoadjuvant Therapy in Postmenopausal Women | 73 |
Panel Discussion 1 | Therapy in Postmenopausal Women | 87 |
Chapter 7 | Endocrine Therapy for Advanced Breast Cancer in Premenopausal Women | 105 |
Chapter 8 | Adjuvant Endocrine Treatment in Premenopausal Patients | 115 |
Chapter 9 | Adjuvant Chemotherapy in Breast Cancer Patients with Hormone-Receptor-Positive (Responsive) Disease: Focus on Premenopausal Women | 127 |
Panel Discussion 2 | Therapy in Premenopausal Women | 137 |
Chapter 10 | Biology of Premalignant Lesions and Pathogenesis | 153 |
Chapter 11 | Estradiol-Induced Carcinogenesis via Formation of Genotoxic Metabolites | |
Chapter 12 | Beyond Tamoxifen: Results of Clinical Trials | 179 |
Chapter 13 | Clinical Trials with Aromatase Inhibitors for the Prevention of Breast Cancer | 189 |
Panel Discussion 3 | Chemoprevention | 203 |
Chapter 14 | Crosstalk Between Estrogen-Receptor and Growth-Factor-Receptor Pathways as a Mechanism of Endocrine Therapy Resistance | 215 |
Chapter 15 | ErbB2/HER-2 and Other Molecular Pathways in Estrogen-Receptor-Positive Breast Cancer: Impact on Endocrine Resistance and Clinical Outcome | 229 |
Chapter 16 | Beyond Antihormones in the Targeted Therapy of Breast Cancer | |
Chapter 17 | Novel Therapeutics | 259 |
Chapter 18 | Surrogate Biomarkers and Neoadjuvant Endocrine Therapy | 269 |
Chapter 19 | Aromatase Localization in Human Breast Cancer with Development of New Antibodies | |
Panel Discussion 4 | Biology and New Therapeutics | 287 |
Panel Discussion 5 | Final Discussion and Wrap-up | 295 |
Index | 311 |
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Add Endocrine Therapy for Breast Cancer, Because of the predominant role estrogens play in the development of breast cancer and the limited effectiveness of tamoxifen therapy, more selective therapeutics targeting estrogen signaling have been developed: selective estrogen receptor modulators (SE, Endocrine Therapy for Breast Cancer to your collection on WonderClub |