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Drug Permeation Enhancement: Theory and Applications, Vol. 62 Book

Drug Permeation Enhancement: Theory and Applications, Vol. 62
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Drug Permeation Enhancement: Theory and Applications, Vol. 62, , Drug Permeation Enhancement: Theory and Applications, Vol. 62
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  • Drug Permeation Enhancement: Theory and Applications, Vol. 62
  • Written by author Hsieh
  • Published by Informa Healthcare, January 1994
  • Providing a comprehensive review of drug permeation enhancement, this reference covers the fundamental aspects of physical and chemical enhancement for the transport of both peptides and nonpeptides through the skin, mucosae, and cornea.;Expanding the fro
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Authors

Preface
Contributors
1Understanding Permeation Enhancement Technologies3
2Skin Penetration Enhancers: Scientific Perspectives19
3Basic Mechanisms in Transepithelium Transport Enhancement25
4Skin Permeation Enhancement Reversibility43
5Visualization of Drug Transport Across Human Skin and the Influence of Penetration Enhancers59
6Compatibility and Synergy of Permeation Enhancers with Solvents, Excipients, and Drugs91
7A General Method for Assessing Skin Permeation Enhancement Mechanisms and Optimization
8Permeation Enhancement with Ethanol: Mechanism of Action Through Skin143
9Liposomes as Penetration Promoters and Localizers of Topically Applied Drugs171
10Barrier Properties of the Skin: Skin Development and Permeation199
11Iontophoresis: Fundamentals219
12Transdermal Delivery of Proteins and Peptides by Iontophoresis: Development, Challenges, and Opportunities247
13In Vivo Experience with Electrically Mediated Transdermal Drug Delivery273
14In Vivo and In Vitro Characteristics of Electro-Transdermal Drug Delivery285
15Transdermal Drug Delivery by Phonophoresis: Basics, Mechanisms, and Techniques of Application303
16Permeability and Metabolism as Barriers to Transmucosal Delivery of Peptides and Proteins323
17Toxicological Evaluation of Intranasal Peptide and Protein Drugs345
18Permeation Enhancement for Ocular Route of Polypeptide Administration385
19Mechanisms of Ocular Peptide Absorption and Its Enhancement397
Index411


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