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Preface | ||
Contributors | ||
1 | Understanding Permeation Enhancement Technologies | 3 |
2 | Skin Penetration Enhancers: Scientific Perspectives | 19 |
3 | Basic Mechanisms in Transepithelium Transport Enhancement | 25 |
4 | Skin Permeation Enhancement Reversibility | 43 |
5 | Visualization of Drug Transport Across Human Skin and the Influence of Penetration Enhancers | 59 |
6 | Compatibility and Synergy of Permeation Enhancers with Solvents, Excipients, and Drugs | 91 |
7 | A General Method for Assessing Skin Permeation Enhancement Mechanisms and Optimization | |
8 | Permeation Enhancement with Ethanol: Mechanism of Action Through Skin | 143 |
9 | Liposomes as Penetration Promoters and Localizers of Topically Applied Drugs | 171 |
10 | Barrier Properties of the Skin: Skin Development and Permeation | 199 |
11 | Iontophoresis: Fundamentals | 219 |
12 | Transdermal Delivery of Proteins and Peptides by Iontophoresis: Development, Challenges, and Opportunities | 247 |
13 | In Vivo Experience with Electrically Mediated Transdermal Drug Delivery | 273 |
14 | In Vivo and In Vitro Characteristics of Electro-Transdermal Drug Delivery | 285 |
15 | Transdermal Drug Delivery by Phonophoresis: Basics, Mechanisms, and Techniques of Application | 303 |
16 | Permeability and Metabolism as Barriers to Transmucosal Delivery of Peptides and Proteins | 323 |
17 | Toxicological Evaluation of Intranasal Peptide and Protein Drugs | 345 |
18 | Permeation Enhancement for Ocular Route of Polypeptide Administration | 385 |
19 | Mechanisms of Ocular Peptide Absorption and Its Enhancement | 397 |
Index | 411 |
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