Cytokines and Chemokines in Infectious Diseases Handbook Book

Introduction: Cytokine Biology Relevant to Infectious Diseases

Charles A. Dinarello

I. Cytokines in Infectious Diseases

Leptin: Its Role in Immunomodulation and Susceptibility to Infection

Graham Lord

Cytokine Gene Polymorphism and Host Susceptibility to Infection

Frank Stüber

II. Cytokines in Gram-Negative Infections

Proinflammatory and Anti-Inflammatory Cytokines as Mediators of Gram-Negative Sepsis

Jean-Marc Cavaillon

Host Response to Pathogenic Bacteria at Mucosal Sites

Laurence Arbibe and Philippe Sansonetti

Macrophage Migration Inhibitory Factor as a Cytokine of Innate Immunity

Thierry Calandra

III. Cytokines in Gram-Positive Infections

Cytokine Patterns in Severe Invasive Group A Strepoccal Infections

Anna Norrby-Teglund and Malak Kotb

Superantigens and Bacterial DNA as Cytokine Inducers in Gram-PositiveSepsis

Klaus Heeg

Cytokines and Chemokines in Listeriosis

Michael S. Rolph and Stefan H. E. Kaufmann

IV. Cytokines in Mycobacterial Infections

Regulation of Cytokines and Chemokines Responses in Human Mycobacterium tuberculosis Infection

Zahra Toossi and Jerrold J. Ellner

Cytokines and Chemokines in Protective and Inflammatory Responses to Infection with Nontuberculous Mycobacteria

Stefan Ehlers

Human Interleukin-12-Interferon-g Axis in Protective Immunity to Mycobacteria

Claire Fieschi, Stéphanie Dupuis, Capucine Picard, and Jean-Laurent Casanova

Role of Th1 Cytokines in Host Defenses Against Mycobacterium leprae

Elizabeth Pereira Sampaio, Milton Ozorio Moraes, M. Cristina Vidal Pessolani, and Euzenir Nunes Sarno

V. Cytokines in Other Bacterial Infections

Possible Role of Molecular Mimicry in Lyme Arthritis

Abbie L. Meyer and Brigitte T. Huber

Cytokine Responses in Patients with Pneumonia

Peter Kragsbjerg and Hans Holmberg

VI. Cytokines in Fungal Infections

Cytokines and the Host Defense Against Aspergillus fumigatus

Emmanuel Roilides, Joanna Filioti, and Cristina Gil-Lamaignere

Cytokines of Innate and Adaptive Immunity to Candida albicans

Luigina Romani

VII. Cytokines in Parasitic Infections

Th1 and Th2 Cytokines in Leishmaniasis

Fabienne Tacchini-Cottier, Geneviève Milon, and Jacques A. Louis

Cytokines in the Regulation of Innate and Adaptive Immunity to Toxoplasma gondii

Ulrike Wille and Christopher A. Hunter

VIII. Cytokines in Viral Infections

Viroceptors: Virus-Encoded Receptors for Cytokines and Chemokines

Grant McFadden

Chemokines and Chemokine Receptors in HIV Infection

Paolo Lusso

Cytokines in Viral Hepatitis

Mala K. Maini and Antonio Bertoletti

IX. Cytokines as Therapeutic Agents in Infectious Diseases

Interferon-g in the Treatment of Infectious Diseases

Steven M. Holland and John I. Gallin

Interleukin-2 for the Treatment of HIV Infection

Guido Poli, Claudio Fortis, Adriano Lazzarin, and Giuseppe Tambussi

Clinical Applications of G-CSF and GM-CSF in the Treatment of Infectious Diseases

Kai Hübel, David C. Dale, Richard K. Root, and W. Conrad Liles

X. Anticytokine-Based Therapy in Treatment of Infectious Diseases

Anticytokine Therapies in Patients with Severe Sepsis and Septic Shock

Pierre-Yves Bochud, Michel P. Glauser, and Thierry Calandra

Intravenous Immunoglobulin Adjunctive Therapy in Patients with Strepoccal Toxic Shock Syndrome and Necrotizing Fasciitis

Anna Norrby-Teglund, Donald E. Low, and Malak Kotb

Index