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Introduction: Cancer and Time | 3 | |
Ch. 1 | The Molecular and Neurophysiologic Basis for Circadian Timekeeping | 11 |
Ch. 2 | Experimental Background for Cancer Chronotherapy | 19 |
Ch. 3 | Neuroendocrine Aspects of Circadian Pharmacodynamics | 43 |
Ch. 4 | Pharmacologic Basis for Circadian Pharmacodynamics | 61 |
Ch. 5 | Circadian Cytokinetics of Murine and Human Gut: Implications for Colon Cancer Chemotherapy | 105 |
Ch. 6 | Circadian Cytokinetics of Murine and Human Bone Marrow and Human Cancer | 119 |
Ch. 7 | Circadian and Ultradian Cytokinetics of Human Cancers | 165 |
Ch. 8 | Chronopharmacodynamics of Hematopoietic Growth Factors and Antitumor Cytokines | 185 |
Ch. 9 | Preclinical Trials of Cancer Chronotherapy | 211 |
Ch. 10 | Cancer Chronotherapy | 241 |
Ch. 11 | Chronotherapeutic Drug Delivery Systems and Devices | 265 |
Epilogue: Implications of Rhythmic Biodynamics for Science, Cancer Drug, and Cancer Therapy Development | 279 | |
Index | 283 |
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