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Cancer Therapy: Radiolabeled Antibodies Book

Cancer Therapy: Radiolabeled Antibodies
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Cancer Therapy: Radiolabeled Antibodies, Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading , Cancer Therapy: Radiolabeled Antibodies
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  • Cancer Therapy: Radiolabeled Antibodies
  • Written by author David M. Goldenberg
  • Published by CRC Press, 11/22/1994
  • Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading
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Ch. 1 Introduction 1
Radiobiology, Radiation Physics, and Dosimetry
Ch. 2 Medical Internal Dosimetry for High-Dose Radionuclide Therapies 7
Ch. 3 Radiolabeled Antibody Tumor Dosimetry 21
Ch. 4 Radiobiology and Radioimmunotherapy: Implications for Clinical Applications 33
Radiochemistry of Therapeutic Radionuclides
Ch. 5 Radiochemistry of Therapeutic Radionuclides 47
Ch. 6 Advanced Methods for Radiolabeling Monoclonal Antibodies with Therapeutic Radionuclides 63
Ch. 7 Antibody Radiolabeling with Isotopes of Rhenium 77
Targeting, Pharmacokinetics, and Experimental Radioimmunotherapy
Ch. 8 Pharmacokinetics of Antibodies and their Radiolabels 89
Ch. 9 Development of Cancer Radioimmunotherapy and its Potential Use as an Adjuvant Treatment 101
Ch. 10 Experimental Radioimmunotherapy and Methods to Increase Therapeutic Efficacy 115
Clinical Radioimmunotherapy
Ch. 11 Overview of Obstacles and Opportunities for Radioimmunotherapy of Cancer 141
Ch. 12 Radioimmunotherapy of Ovarian Cancer 155
Ch. 13 Radioimmunotherapy of Colorectal Cancer 173
Ch. 14 Radioimmunotherapy in the Treatment of Metastatic Breast Cancer: An Overview 189
Ch. 15 Radioimmunotherapy of CNS Malignant Gliomas by Direct Intralesional Injection of Specific [superscript 131]I Radiolabeled Monoclonal Antibodies
Ch. 16 Treatment of B-Lymphocyte Malignancies with [superscript 131]I-Lym-1-and [superscript 67]Cu-2IT-BAT-Lym-1 and Opportunities for Improvement 217
Ch. 17 Treatment of Relapsed B Cell Lymphomas with High-Dose Radioimmunotherapy and Bone Marrow Transplantation 229
New Strategies
Ch. 18 Clinical Application of the Avidin-Biotin System for Tumor Targeting 239
Ch. 19 Humanization of Monoclonal Antibodies: Molecular Approaches and Applications 255
Ch. 20 Human Monoclonal Antibodies: Application in Radioimmunotherapy 271
Ch. 21 Cytokine-Based Modalities to Enhance Monoclonal-Antibody-Mediated Tumor Cell Killing 283
Ch. 22 Overcoming Dose-Limiting, Antibody-Induced Myelotoxicity 295
Index 315


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Cancer Therapy: Radiolabeled Antibodies, Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading , Cancer Therapy: Radiolabeled Antibodies

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Cancer Therapy: Radiolabeled Antibodies, Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading , Cancer Therapy: Radiolabeled Antibodies

Cancer Therapy: Radiolabeled Antibodies

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Cancer Therapy: Radiolabeled Antibodies, Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading , Cancer Therapy: Radiolabeled Antibodies

Cancer Therapy: Radiolabeled Antibodies

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