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A comprehensive discussion of cancer's effect on the skeleton, this book covers bone tumors, myeloma bone disease and bone metastases. It discusses assessment of these conditions through diagnostic imaging and the use of bone markers and their treatment through the bisphosphonates. The two editors, both experts in the field, have assembled an international team of contributors whose names will be instantly recognized by those specializing in the fields of bone oncology in particular and metabolic bone disease in general.
This is a thorough review of bone metastases in malignancy with complete discussions on the pathophysiology, diagnosis. complications, and treatment of metastatic bone disease. The emphasis is on presenting the most recent advances in this complex field. This includes the most up-to-date knowledge of both normal and metastatic bone physiology, as well as updates on the increasingly expanding role of bisphosphonates in the management of myeloma and solid tumor metastatic disease. This is an extremely valuable text for oncologists, orthopedic oncologists, endocrinologists, and anyone with an interest in bone metastases in cancer. The editors are well known experts in oncology and bone metabolism, and they have brought together a diverse array of internationally known experts, who have written excellent individual chapters. This book is extremely thorough, with detailed discussions of all appropriate imaging techniques. There are several chapters encompassing management of bone metastases, including individual discussions on bisphosphonates, radioisotopes, radiation, surgical management, and an entire chapter on the pathophysiology and management of hypercalcemia. There is also appropriate detailed attention to the management of pain that is caused by bone metastases. The tables and figures are well-organized and instructive, and the index is also helpful. This is an outstanding text that should be included in the libraries of all those with an interest in the physiology, diagnosis, and/or management of patients presented with the difficult problem of cancer that is metastatic to bones.
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