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Bone Morphogenetics Proteins : From Local to Systemic Therapeutics Book

Bone Morphogenetics Proteins : From Local to Systemic Therapeutics
Bone Morphogenetics Proteins : From Local to Systemic Therapeutics, Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal, Bone Morphogenetics Proteins : From Local to Systemic Therapeutics has a rating of 4 stars
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Bone Morphogenetics Proteins : From Local to Systemic Therapeutics, Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal, Bone Morphogenetics Proteins : From Local to Systemic Therapeutics
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  • Bone Morphogenetics Proteins : From Local to Systemic Therapeutics
  • Written by author Slobodan Vukicevic
  • Published by Springer-Verlag New York, LLC, July 2008
  • Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal
  • Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal
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Authors

List of contributors vii

Preface xi

Introduction Slobodan Vukicevic Kuber Sampath 1

Development of a novel compression-resistant carrier for recombinant human bone morphogenetic protein-2 (rhBMP-2) and preliminary clinical results William F. McKay Steven M. Peckham Jeffrey M. Badura 7

Use of recombinant human BMP-2 in orthopedic trauma Michael Suk 25

The application of recombinant human bone morphogenetic protein on absorbable collagen sponge (rhBMP-2/ACS) to reconstruction of maxillofacial bone defects Daniel B. Spagnoli 43

Clinical outcomes using rhBMP-2 in spinal fusion applications J. Kenneth Burkus 71

Bone morphogenetic protein signaling is fine-tuned on multiple levels Christina Sieber Gerburg K. Schwaerzer Petra Knaus 81

Dissection of bone morphogenetic protein signaling using genome engineering tools Daniel Graf Aris N. Economides 115

Alterations of bone morphogenetic protein signaling pathway(s) in skeletal diseases Petra Seemann Stefan Mundlos Katarina Lehmann 141

Signaling crosstalk by bone morphogenetic proteins Nandini Ghosh-Choudhury Goutam Ghosh-Choudhury 161

The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development Stephen E. Harris Wuchen Yang Jelica Gluhak-Heinrich Dayong Guo Xiao-Dong Chen Marie A. Harris Holger Kulessa Brigid L.M. Hogan|cAlexander Lichtler Barbara E. Kream Jianhong Zhang Jian Q. Feng Gregory R. Mundy James Edwards Yuji Mishina 179

The role of bone morphogenetic protein 4 (BMP-4) in tooth development Jelica Gluhak-Heinrich Dayong Guo Wuchen Yang Lilia E. Martinez Marie A. Harris Holger Kulessa Brigid L.M. Hogan Alexander Lichtler Barbara Kream Jianhong Zhang Jian Q. FengStephen E. Harris 199

Bone morphogenetic protein antagonists and kidney Motoko Yanagita 213

Induction of cementogenesis and periodontal ligament regeneration by the bone morphogenetic proteins Ugo Ripamonti Jean-Claude Petit June Teare 233

Control of bone mass by sclerostin: inhibiting BMP- and WNT-induced bone formation David J.J. de Gorter Carola Krause Clemens W.G.M. Lowik Rutger L. van Bezooijen Peter ten Dijke 257

Bone morphogenetic proteins in cartilage biology Susan Chubinskaya Mark Hurtig David C. Rueger 277

Systemic administration of bone morphogenetic proteins Slobodan Vukicevic Petra Simic Lovorka Grgurevic Fran Borovecki Kuber Sampath 317

Index 339


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Bone Morphogenetics Proteins : From Local to Systemic Therapeutics, Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal, Bone Morphogenetics Proteins : From Local to Systemic Therapeutics

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