Blueprints Infectious Diseases Book

	Contributors	xi
	Reviewers	xv
	Preface	xvii
	Acknowledgments	xviii
	Abbreviations	xix
Chapter 1	Diagnostic Microbiology	1
	Laboratory Methods Used to Identify Bacteria	1
	Laboratory Methods Used to Identify Fungi	4
	Laboratory Methods Used to Identify Parasites	4
	Antibiotic Susceptibility Testing	5
Chapter 2	Clinical and Diagnostic Virology	9
	Typical Virus Classification	9
	Diagnosis	9
	Human Herpesviruses (HHV)	9
	Herpes Simplex Virus, Type 1 (HSV-1)	10
	Herpes Simplex Virus, Type 2 (HSV-2)	10
	Varicella-Zoster Virus (VZV)	10
	Epstein-Barr Virus (EBV)	11
	Cytomegalovirus (CMV)	11
	HHV-6/7	11
	HHV-8 (Kaposi's Sarcoma-Associated Herpesvirus)	11
	Respiratory Viruses	12
	Influenza	12
	Respiratory Syncytial Virus	12
	Adenovirus	12
	Parainfluenza	13
	Rhinovirus	13
	Metapneumovirus	13
	Coronaviruses	13
	SARS	13
	Gastrointestinal Viruses	14
	Enteroviruses	14
	Poliovirus	14
	Echovirus/Coxsackievirus/Other Enteroviruses	14
	Poxviruses and Papillomaviruses	15
	Smallpox (Variola), Other Orthopox, and Parapox Viruses	15
	Papillomaviruses	15
	Polyomaviruses	15
	Measles/Mumps/Rubella	16
	Measles (Rubeola)	16
	Mumps	16
	Rubella (German Measles)	16
	Parvovirus	16
	Rabies	17
	Flaviviruses	17
	West Nile	17
	Dengue	17
	Yellow Fever	18
	Other Flaviviruses	18
	Hemorrhagic Viruses	18
	Filoviridae	18
	Bunyaviridae	18
	Arenaviruses	19
	Retroviruses	19
	HTLV-1 and -2	19
Chapter 3	Antimicrobial Agents	20
Chapter 4	Antifungal Agents	26
	Antifungal Agents Used for Treatment of Invasive Fungal Infections	26
	Polyenes	26
	Triazoles	28
	Echinocandins	29
	Flucytosine	30
	Antifungals Used for Treatment of Skin and Mucosal Fungal Infections	30
	Griseofulvin	30
	Allylamines	31
	Imidazoles	32
	Polyenes	32
Chapter 5	Antiviral Agents Including Antiretrovirals	33
	Antiviral Agents	33
	Influenza Antivirals	33
	Herpesvirus Antivirals	34
	Antiretroviral Agents	35
	Nucleoside Reverse Transcriptase Inhibitors (NRTIs)	36
	Nucleotide Reverse Transcriptase Inhibitors (NtRTI)	37
	Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)	37
	Protease Inhibitors	37
	Fusion Inhibitor	38
	Interferons	38
Chapter 6	Ophthalmologic Infections	39
	Infectious Conjunctivitis	39
	Infectious Keratitis	43
	Infectious Endophthalmitis	44
	Extraocular/Orbital Infection	49
Chapter 7	Central Nervous System Infections	53
	Meningitis	53
	Encephalitis	56
	Brain and Parameningeal Abscesses	60
	Ventricular Shunt Infections	62
Chapter 8	Ear, Nose, and Throat Infections	64
	Otitis	64
	Sinusitis (Rhinosinusitis)	66
	Pharyngitis	68
Chapter 9	Respiratory Tract Infections	70
	Bronchitis	70
	Pleural Effusions	71
	Community-Acquired Pneumonia	73
	Tuberculosis	80
Chapter 10	Cardiac Infections	83
	Endocarditis	83
	Myocarditis	86
	Pericarditis	89
Chapter 11	Gastrointestinal Infections	92
	Hepatitis A Virus	92
	Hepatitis B Virus	93
	Hepatitis C Virus	94
	Hepatitis D Virus (HDV)	96
	Hepatitis E Virus	96
	Infectious Diarrhea	96
	Clostridium difficile	98
Chapter 12	Genitourinary Tract Infections	101
	Urinary Tract Infections	101
	Genital Skin/Mucosal Lesions	103
	Pelvic Inflammatory Disease and Cervicitis	104
	Urethritis	106
	Syphilis	107
	Genital Herpes: HSV	108
Chapter 13	Skin and Soft Tissue Infections	111
	Streptococcal and Staphylococcal Skin Infections	111
	Folliculitis	112
	Cutaneous Abscesses	114
	Cellulitis	114
	Infected Animal Bites	116
	Infected Human Bites	118
	Necrotizing Fasciitis	119
Chapter 14	Bone and Joint Infections	122
	Septic Arthritis	122
	Osteomyelitis	124
Chapter 15	Bloodstream Infections	127
	Sepsis	127
	Central Venous Catheter-Related Infection	129
	Toxic Shock Syndrome	133
Chapter 16	Human Immunodeficiency Virus	137
Chapter 17	Infections in Special Hosts	146
	Fever and Neutropenia	146
	Infections in Solid Organ Transplants	150
	Infections in Bone Marrow Transplants	155
	Postsplenectomy Sepsis	157
	Infections During Pregnancy-Bacteriuria	158
Chapter 18	Fever	161
	Fever of Unknown Origin (FUO)	161
	Hereditary Periodic Fever Syndromes	165
	Tick-Borne Illnesses	167
Chapter 19	Travel Medicine	175
	Pretravel Preparation	175
	Malaria	179
	Traveler's Diarrhea and Intestinal Parasites	182
	Fever in the Returning Traveler	183
Chapter 20	Biowarfare Agents	187
	Anthrax	187
	Plague	190
	Smallpox	192
	Tularemia	194
Chapter 21	Prevention of Infection	197
	Passive Immunization	197
	Active Immunization	199
	Chemoprophylaxis	204
	Needle-Stick Injury	208
	Infection Control	209
Appendix A	Opportunities in Internal Medicine and Adult Infectious Diseases	212
Appendix B	Review Questions and Answers	214
Appendix C	Commonly Prescribed Medications	234
Appendix D	Diagnostic Tests by Clinical Syndrome	235
Appendix E	Evidence-Based Resources	243
	Index	249