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List of contributors vii
Introduction
Introduction Marco Baggiolini 3
Cellular targets in innate and adaptive immunity
Traffic of T lymphocytes Charles Mackay Bernhard Moser 19
Lymphocyte homing to peripheral epithelial tissues William W. Agace Bernhard Homey 35
Chemokine biology of NK cells and [gamma delta] T cells Chenggang Jin Craig T. Morita 59
Dendritic cell traffic control by chemokines Federica Sallusto Alfonso Martin-Fontecha Antonio Lanzavecchia 79
Chemokine receptor-mediated signal transduction Mario Mellado Carlos Martinez-A. Jose Miguel Rodriguez-Frade 91
Chemokines in leukocyte transendothelial migration Lixin Liu Paul Kubes 109
Natural chemokine antagonism and synergism Mariagrazia Uguccioni Basil O. Gerber 123
Effector cell traffic-unrelated functions
Crosstalk between chemokine, opioid and vanilloid receptors Ning Zhang Joost J. Oppenheim 137
Antimicrobial and related activities of chemokines Osamu Yoshie 151
Virus-encoded chemokine modulators as novel anti-inflammatory reagents Alexandra Lucas Dana McIvor Grant MacFadden 165
Chemokine receptors in tissue cells and angiogenesis Paola Romagnani Laura Lasagni Sergio Romagnani 183
Index 205
| Price | Condition | Delivery | Seller | Action |
| $179.00 | Digital |
| WonderClub |
Jay Ellison
reviewed Chemokine Biology: Basic Research and Clinical Applications on January 14, 2009
Chemokine Biology
Very nice read. Describes the often tumultuous political scene that underlay the Human Genome Sequencing project.
Originally the Human Genome project was publicly funded, and included many of the brightest human geneticists in the world. In addition to being brilliant scientists, this group contained some fascinating personalities. The author does an excellent job of conveying these often extreme personalities and setting the scene for what would eventually escalate into the scientific equivalent of all out nuclear war.
The story really gets interesting when a rogue geneticist name J. Craig Venter decides to leave the public consortium and join a corporate venture with the intention of beating the public scientists to the prize. Most of the book tracks Venter and story. He is a fascinatingly conflicted character, equal parts megalomaniac and saint.
The book delves into the science in an approachable manner. This is pretty interesting in its own right, but the real story is the brinksmanship between the public and private sequencing groups.
Overall if you are interested in learning about human genomics and like a battle of the titans plot line this is the book for you
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