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| List of Contributors | ||
| Preface | ||
| Ch. 1 | Prologue | 1 |
| Ch. 2 | B Cells, Immunoglobulin Genes and Variable Gene Utilization by Autoantibodies | 15 |
| Ch. 3 | CD5-Ly1 B Cells and Autoimmunity | 31 |
| Ch. 4 | Natural Antibodies | 45 |
| Ch. 5 | Expression and Pairing of VH and VL Families in Murine and Human Self-reactive Antibodies | 65 |
| Ch. 6 | Antigen Presentation of Self Antigens | 83 |
| Ch. 7 | The Role of the MHC in Autoimmune Disease | 101 |
| Ch. 8 | T Cell Antigen Receptor and Autoimmunity | 113 |
| Ch. 9 | Signal Transduction Pathways in T Lymphocytes and Their Relevance to Autoimmunity | 137 |
| Ch. 10 | Cytokines and Autoimmunity | 149 |
| Ch. 11 | T Cell Adhesion Molecules: Relevance to Autoimmunity | 169 |
| Ch. 12 | The Effect of Natural Killer Cells on Autoimmunity | 179 |
| Ch. 13 | The Role of Fc[gamma]Rs in Autoimmunity | 191 |
| Ch. 14 | Tolerance | 195 |
| Ch. 15 | Transgenic Models of Autoimmune Disease | 205 |
| Ch. 16 | Idiotypy and the Idiotype Network in Autoimmunity | 209 |
| Ch. 17 | Immune Complexes in Autoimmunity | 229 |
| Ch. 18 | Bacterial Antigen Mimicry | 245 |
| Antigenic Mimicry | 257 | |
| Ch. 19 | Human Systemic Lupus Erythematosus | 265 |
| Immunologic Genes in Mouse Lupus Models | 281 | |
| Ch. 20 | Sjogren's Syndrome: An Autoimmune Exocrinopathy | 317 |
| Experimental Models of Sjogren's Syndrome | 333 | |
| Ch. 21 | Rheumatoid Arthritis | 347 |
| Collagen-Induced Arthritis: Animal Model and Clinical Relevance | 363 | |
| Ch. 22 | Systemic Sclerosis | 377 |
| Experimental Models for Scleroderma | 401 | |
| Ch. 23 | Idiopathic Inflammatory Myopathies | 415 |
| Ch. 24 | Molecular Pathology of Autoimmunity in Systemic Vasculitis | 425 |
| Ch. 25 | Autoimmune Hemolytic Anemia | 439 |
| Experimental Models of Autoimmune Hemolytic Anemia | 451 | |
| Ch. 26 | Autoimmune Thrombocytopenic Purpura | 471 |
| Experimental Autoimmune Thrombocytopenic Purpura | 487 | |
| Ch. 27 | Autoimmunity in Hashimoto's Disease | 493 |
| Immunological Mechanisms in Graves' Disease | 511 | |
| Ch. 28 | Myasthenia Gravis | 541 |
| Ch. 29 | Vitiligo | 555 |
| Pemphigus | 563 | |
| Ch. 30 | The Cellular and Molecular Pathology of Multiple Sclerosis | 575 |
| Experimental Allergic Encephalomyelitis | 585 | |
| Ch. 31 | Human Autoimmune Diabetes | 601 |
| Animal Models of Insulin Dependent Diabetes Mellitus | 619 | |
| Ch. 32 | Molecular Biology of Autoantigens in Primary Biliary Cirrhosis | 629 |
| Ch. 33 | Immunoregulatory Defects in Inflammatory Bowel Disease | 643 |
| Ch. 34 | Autoimmune Diseases of the Retina | 651 |
| Ch. 35 | Autoimmune Renal Disease | 673 |
| Ch. 36 | Autoimmune Diseases of the Reproductive Tract | 705 |
| Ch. 37 | Immunologic Aspects of Otologic Disease | 715 |
| Ch. 38 | AIDS and Autoimmunity | 727 |
| Ch. 39 | Transplantation and Autoimmunity | 751 |
| Ch. 40 | The Nature and Significance of Age-associated Autoimmunity | 765 |
| Ch. 41 | Therapy of Autoimmune Diseases | 777 |
| Index | 793 |
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