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The object of this book is to summarize the known facts and current hypotheses about the biomedical significance of oxidative stress in dermatology. In an introduction, the physicochemical properties and production and target sites of reactive oxidants in the skin are discussed. The antioxidant systems of the skin are then described, and the participation of oxidants and antioxidants in basic pathophysiologicevents is analyzed. Finally, specific aspects of oxidative injury in selected skin diseases,
pharmacology and toxicology are investigated. the book thus deals comprehensively with many areas of cutaneous biology andclinical dermatology from the perspective of a "free radical" scientist and physician, and should serve as a
"cornerstone" in this rapidly changing areaof cutaneous biology research.
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