Nucleic acids Book

Group VII of the Landolt-Bornstein New Series is devoted to the physical properties of biological systems. It begins with volume VII/1 covering the nucleic acids which are of central importance in all processes involving gene expression. This field has become of practical consequence during the last decade through the development of genetic engineering. Because of the amount of the data available, volume VII/1 had to be divided into several subvolumes. The first two subvolumes, VII/1a and VII/1b, deal with crystallographic and structural data which give a comprehensive information on the three-dimensional structure of the nucleic acids, their folding properties, their hydrogen bonding sciences, their metal binding capabilities, their hydration and their drug complexation. Subvolume VII/1a which has just appeared, treats nomenclature and definitions in the field of nucleic acids, followed by the structure data of bases, nucleosides, nucleotides and oligonucleotides. Thereby, the basic foundations of nucleic acid structure are laid in this subvolume. The present subvolume VII/1b is concerned with the relevant data on fiber structures of DNA and RNA, on complexes between nucleotides and metal-ions and between oligonucleotides and drugs, and on hydrogen bonding of the nucleic acid constituents.