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Acronyms and Abbreviations List of Tables Introduction Acknowledgements
1. The Nature of Tranquillizing Drugs Introduction The Demand for a Quiet Life For a Few Profits More Beyond Barbiturates Too Much of a 'Good Thing': Benzodiazepine Accumulation and Dependence Conclusion
2. The Political Control of Medicines Introduction Governments as Drug Safety Watchdogs The Food and Drug Administration: American Regulation Gets Serious The British Department of Health: Secrets and Shoestrings Who is Government's Best Friend: Industry or Consumers?
Conclusion
3. The Rise of Halcion: Getting Approval Introduction British Acceptance of Halcion The Dutch Crisis Mobilizing American Approval Halcion is Number One Conclusion
4. Sounding the Retreat: The Accumulation of Post-Marketing Problems Introduction Not what the Doctor Ordered: Amnesia, Seizures and Hallucinations Assessing the Risks of Halcion: the Food and Drug Administration at War with Itself Compromising Medicine: Safety in Doses?
Blinkering Expert Advice: the Food and Drug Administration Reconsiders Halcion Conclusion
5. Legal Challenge and Loss of Faith: British Medicines Control in Crisis Introduction The Truth is out there: the Grundberg Case The Hottest Data in Town: Protocol 32 1
Enough is Enough: the British Suspend Halcion Making up Data and Other Irregularities: Disqualified Clinical Investigators An Allegation too far: BBC Television Mangolds Upjohn Upjohn's Appeal to the Committee on Safety of Medicines Upjohn's Appeal to the Medicines Commission Upjohn's Appeal to the Panel of Appointed Persons The Medicines Control Agency Decides Conclusion
6. How the West was Won: Keep Taking the Tablets in the United States Introduction Watching the Detectives: the Food and Drug Administration's Inspection of Upjohn Return of the experts: Psychopharmacologica1 Drugs Advisory Committee, 1992
Conflicts of Interest: More than Meets the Eye Justice and the Food and Drug Administration's Conscience A Task for the Super Scientists? The Institute of Medicine Analysis Conclusion
7. Prescription for Change: The Science and Politics of Medicines Control Methodological Appendix Notes Glossary of Tranquillizers Index
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Add The Therapeutic Nightmare : The Battle over the World's Most Controversial Tranquilizer, 'Brilliantly documents how the flawed drug industry/government axis allows Halcion and other dangerous, but real, nightmares to be approved and widely used. The book's lessons, if learned and acted upon, can prevent further disasters of this kind from occ, The Therapeutic Nightmare : The Battle over the World's Most Controversial Tranquilizer to the inventory that you are selling on WonderClubX
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Add The Therapeutic Nightmare : The Battle over the World's Most Controversial Tranquilizer, 'Brilliantly documents how the flawed drug industry/government axis allows Halcion and other dangerous, but real, nightmares to be approved and widely used. The book's lessons, if learned and acted upon, can prevent further disasters of this kind from occ, The Therapeutic Nightmare : The Battle over the World's Most Controversial Tranquilizer to your collection on WonderClub |