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Thyroid Cancer Book

Thyroid Cancer
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  • Thyroid Cancer
  • Written by author Leonard Wartofsky
  • Published by Springer-Verlag New York, LLC, June 2005
  • Intended for both pathologists and endocrinologists, this reference collects the different approaches required to manage papillary carcinoma, follicular carcinoma, medullary thyroid carcinoma, thyroid lymphomas, and anaplastic cancers. For each tumor type
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1Anatomy and physiology of the thyroid gland : clinical correlates to thyroid cancer3
2Epidemiology of thyroid cancer9
3Molecular pathogenesis of thyroid cancer15
4Molecular aspects of thyroid cancer in children33
5Oncogenes in thyroid cancer41
6Apoptosis in thyroid cancer55
7Radiation-induced thyroid cancer63
8Classification of thyroid malignancies85
9Staging of thyroid cancer87
10Thyroid cancer in children and adolescents97
11Recombinant human thyrotropin103
12History of the role of nuclear medicine in the thyroid gland and its diseases : a personal perspective117
13Prophylaxis against radiation exposure from radioiodine129
14Radioiodine whole body imaging133
15Primer and atlas for the interpretation of radioiodine whole-body scintigraphy151
16False-positive radioiodine scans in thyroid cancer
17The thyroid nodule : evaluation, risk of malignancy, and management201
18Fine needle aspiration : technique211
19Thyroid nodules : cellular and biochemical markers for malignancy213
20Radionuclide imaging of thyroid nodules223
21Ultrasonic imaging of the neck in patients with thyroid cancer229
22Thyroid nodules and cancer risk : surgical management247
23Papillary cancer : clinical aspects253
24Surgical approach to papillary cancer261
25Papillary carcinoma : cytology and pathology263
26Prescribed activity for radioiodine ablation273
27Thyroid remnant radioiodine ablation with recombinant human thyrotropin283
28Follow-up strategy in papillary thyroid cancer289
29Levothyroxine therapy and thyrotropin suppression293
30Thyroglobulin and thyroglobulin antibodies : measurement and interferences297
31Diagnosis of recurrent thyroid cancer in patients with positive antithyroglobulin antibodies305
32Surveillance radioiodine whole-body scans309
33Radionuclide imaging and treatment of thyroid cancer in children313
34Positron emission tomography in well-differentiated thyroid cancer319
35Alternative thyroid imaging329
36The "stunning" controversy
AStunning : untoward effect of [superscript 131]I thyroid imaging prior to radioablation therapy337
BStunning is not a problem346
CStunning : does it exist? A commentary349
37Ultrasonic imaging and identification of metastases in cervical lymph nodes351
38Magnetic resonance imaging and computed tomography imaging of thyroid cancer359
39Management of the patient with negative radioiodine scan and elevated serum thyroglobulin367
40Determinants of prognosis in papillary thyroid carcinoma375
41Papillary cancer : special aspects in children377
42Special presentations of thyroid cancer in pregnancy, renal failure, thyrotoxicosis, and struma ovarii387
43Thyroglossal duct carcinoma393
44Radiation and radioactivity399
45Radioiodine treatment of distant metastases411
46[superscript 131]I treatment of metastatic thyroid carcinoma following preparation by recombinant human thyrotropin427
47Dosimetry : dosimetrically-determined prescribed activity of radioiodine for the treatment of metastatic thyroid carcinoma433
48Radioiodine dosimetry with recombinant human thyrotropin447
49Use of lithium as an adjuvant to radioiodine in the treatment of thyroid cancer453
50Side effects of [superscript 131]I for ablation and treatment of well-differentiated thyroid carcinoma459
51External radiation therapy of papillary cancer485
52AChemotherapy of thyroid cancer : general principles491
52BChemotherapy of well-differentiated papillary or follicular thyroid carcinoma494
53Thyroid carcinoma; metastases to bone497
54Adjunctive local approaches to metastatic thyroid cancer509
55Follicular thyroid cancer : clinical aspects517
56Surgical management of follicular thyroid cancer523
57Pathology of follicular cancer527
58Hurthle cell carcinoma531
59Radionuclide imaging, ablation, and treatment in follicular thyroid carcinoma537
60Follow-up strategy in follicular thyroid cancer539
61PET in follicular cancer, including Hurthle cell cancer541
62Follicular thyroid cancer : special aspects in children and adolescents543
63External radiation therapy of follicular carcinoma545
64Determinants of prognosis in patients with follicular thyroid carcinoma549
65Miscellaneous and unusual types of thyroid cancer553
66Pathology of miscellaneous and unusual cancers of the thyroid571
67Clinical aspects of medullary thyroid carcinoma581
68Pathology of medullary thyroid cancer591
69Medullary carcinoma of the thyroid : surgical management595
70Radionuclide imaging of medullary carcinoma : utility of radiolabeled Somatostatin analogs and other radiotracers597
71PET in medullary thyroid cancer603
72External radiation therapy of medullary cancer605
73Medullary carcinoma of the thyroid : chemotherapy609
74Thyroid lymphoma615
75Pathology of lymphoma of the thyroid621
76FDG-PET scanning in lymphoma and lymphoma of the thyroid623
77Anaplastic carcinoma : clinical aspects629
78Surgical management of anaplastic thyroid carcinoma633
79Pathology of anaplastic carcinoma635
80PET scanning in anaplastic cancer of the thyroid639
81External radiation therapy of anaplastic thyroid cancer641
82Chemotherapy for anaplastic thyroid cancer643
83Anaplastic carcinoma : prognosis647
84Advances in radiation therapy653
85New approaches in nuclear medicine for thyroid cancer657
86Alternative options and future directions for thyroid cancer therapy665
87Potential approaches to chemotherapy of thyroid cancer in the future671
88Low iodine diets677
89Appendix A : books and manuals683
90Appendix B : additional sources of information : support groups, Websites and additional information685
91Appendix C : forms and instructions for patients treated with radioactivity689


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