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| Preface | v | |
| Contributors | ix | |
| 1 | Renal Cytochrome P450s and Flavin-Containing Monooxygenases: Potential Roles in Metabolism and Toxicity of 1,3-Butadiene, Trichloroethylene, and Tetrachloroethylene | 1 |
| 2 | Experimental Approaches for the Study of Cytochrome P450 Gene Regulation | 19 |
| 3 | Insulin and Growth Factor Signaling: Effects on Drug-Metabolizing Enzymes | 45 |
| 4 | Catalytic Function and Expression of Glutathione Transferase Zeta | 85 |
| 5 | Glucuronidation of Fatty Acids and Prostaglandins by Human UDP-Glucuronosyltransferases | 109 |
| 6 | Transcriptional Regulation of UDP-Glucuronosyltransferases | 133 |
| 7 | Phenotypic and Genotypic Characterization of N-Acetylation | 173 |
| 8 | Methods and Approaches to Study Metabolism and Toxicity of Acetaminophen | 197 |
| 9 | Modulation of Drug Metabolism and Antiviral Therapies | 233 |
| 10 | Modulation of Thiols and Other Low-Molecular-Weight Cofactors: Effects on Drug Metabolism and Disease Susceptibility | 253 |
| 11 | Multidrug Resistance Proteins and Hepatic Transport of Endo- and Xenobiotics | 273 |
| 12 | Structural Determinants of Folate and Antifolate Membrane Transport by the Reduced Folate Carrier | 291 |
| 13 | Glutathione Transport in the Kidneys: Experimental Models, Mechanisms, and Methods | 319 |
| 14 | Human Cytosolic Sulfotransferases: Properties, Physiological Functions, and Toxicology | 341 |
| Index | 379 |
| Price | Condition | Delivery | Seller | Action |
| $149.00 | Digital |
| WonderClub |
Seth Johnson
reviewed Drug Metabolism and Transport on August 18, 2014 Drug Metabolism and Transport
This book is something to read if you're interested in learning about the field of bio medical engineering and how far it's come in the past half century. If you're looking for one of those books to read while you're drinking coffee with your book club, I don't think this is it. It's something that only a biological science/medicine lover would pick up. Nothing like the watered down NYT bestsellers that brush over topics. It's more of a historical report on engineering in the life sciences. Even the anecdotes are the kind only a scientist would love. I wish that it were a book I could do the former with, so I'm being petty and withholding two stars.
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