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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease Book

Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease
Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease, , Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease has a rating of 4 stars
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  • Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease
  • Written by author A. Michael Lincoff
  • Published by Springer-Verlag New York, LLC, October 2007
  • A. Michael Lincoff takes advantage of critically important new knowledge arising from recent clinical trials to update and expand his acclaimed Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease. This substantially enhanced Second Edition
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Authors

Preface
Contributors
Pt. IBasic Principles
1Thrombosis in Acute Coronary Syndromes and Coronary Interventions3
2Platelet Adhesion23
3Glycoprotein IIb/IIIa in Platelet Aggregation and Acute Arterial Thrombosis39
4Glycoprotein IIb/IIIa Antagonists: Development of Abciximab and Pharmacology of Abciximab, Tirofiban, and Eptifibatide73
Pt. IIGlycoprotein IIb/IIIa Blockade During Coronary Intervention
5Abeiximab During Percutaneous Coronary Intervention: EPIC, EPILOG, and EPISTENT Trials105
6Eptifibatide in Coronary Intervention: The IMPACT and ESPRIT Trials125
7Tirofiban in Interventional Cardiology: The RESTORE and TARGET Trials147
8Overview of the Glycoprotein IIb/IIIa Interventional Trials167
Pt. IIIGlycoprotein IIb/IIIa Blockade for Acute Ischemic Syndromes
9The Use of Abciximab in Therapy-Resistant Unstable Angina: Clinical and Angiographic Results of the CAPTURE Pilot Trial and the CAPTURE Study203
10Unstable Angina Trials: PARAGON, PURSUIT, PRISM, PRISM-PLUS, and GUSTO-IV233
11Platelet Glycoprotein IIb/IIIa Inhibitors and an Invasive Strategy263
12Glycoprotein IIb/IIIa Receptor Blockade in Myocardial Infarction: Adjunctive Therapy to Percutaneous Coronary Interventions275
13Glycoprotein IIb/IIIa Receptor Blockade in Acute Myocardial Infarction: Adjunctive Therapy to Fibrinolysis289
Pt. IVPractical Issues and Future Applications
14Economics of Glycoprotein IIb/IIIa Inhibition305
15Platelet Monitoring and Interaction of Glycoprotein IIb/IIIa Antagonists with Other Antiplatelet Agents321
16Platelet Glycoprotein IIb/IIa Antagonists: Their Interaction with Low-Molecular-Weight Heparins and Direct Thrombin Inhibitors341
17Oral Agents365
18Platelet Glycoprotein IIb/IIIa Inhibitors: Effects Beyond the Platelet383
19Cerebrovascular Interventions397
20Cerebrovascular Aspects of Glycoprotein IIb/IIIa Receptor Inhibitors409
21Evolution of Drug Development in Evidence-Based Medicine: Summary and the Future425
Index459


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