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Preface | v | |
1. | Opening Lecture | |
Neuroimaging: A Contemporary Approach to Improved Understanding of Mental Illness | 3 | |
2. | Basics of Neuroanatomy | |
Brain Atlases for the 21st Century | 9 | |
Multimodal Mapping of Human Cerebral Cortex--Individual Variability | 16 | |
A Topographic Segmentation of the Cerebral Cortex using MRI | 21 | |
Summary of Discussions--Basics of Neuroanatomy | 28 | |
3. | Structural MRI in Psychiatry | |
Structural Brain Abnormalities in Psychosis | 30 | |
MRI Findings and Clinical Outcomes in Schizophrenia | 34 | |
White Matter Maturation from Birth through Adulthood: A High b Value Diffusion Weighted Imaging Study | 39 | |
Summary of Discussions--Structural MRI in Psychiatry | 44 | |
4. | Connections and Networks | |
DTI and fMRI--Complementary Information | 48 | |
The Importance of Connectivity for Brain Function | 55 | |
DTI: What Does It Mean? | 60 | |
Summary of Discussions--Connections and Networks | 64 | |
5. | Neural Computational Models of Mental Disorders | |
Connectionist Approach in Functional Imaging | 67 | |
Disconnections in Schizophrenia | 73 | |
The Control of Motor Behaviour in Health & Disease: Combining Behavioral and Computational Approaches | 84 | |
Summary of Discussions--Neural Computational Models of Mental Disorders | 90 | |
6. | Opening Lecture | |
Integration of Neurobehavioral Measures: Schizophrenia as a Case Study | 95 | |
7. | Imaging Approaches to Psychiatry | |
Bypassing the Spatial Limits in Human fMRI | 99 | |
Amygdala and Emotional Processing | 105 | |
fMRI in Psychiatry: The Poor Performance Dilemma | 108 | |
Summary of Discussions--Imaging Approaches to Psychiatry | 114 | |
8. | From Neurons to Whole Brain | |
The Role of Neurophysiology in Understanding Psychiatric Illness: The Neural Basis of Action Understanding | 116 | |
Functional Connectivity and EEG | 122 | |
Summary of Discussions--From Neurons to Whole Brain | 129 | |
9. | Imaging of Anxiety and Affective Disorders | |
Neuronal Sensitivity to Negative Emotional Context: Effect of Experience | 131 | |
rCBF PET of Anxiety Disorders--Several Methodological Problems | 143 | |
PET Studies of Depression | 146 | |
Summary of Discussions--Imaging of Anxiety and Affective Disorders | 154 | |
10. | Imaging of Drug Use and Abuse | |
Monitoring Treatment Effects | 156 | |
Functional Neuroanatomy and in vivo Neurochemistry in PTSD | 161 | |
Pharmacological Magnetic Resonance Imaging of Transmitter Mechanisms for Large-scale Brain Adaptivity | 170 | |
Summary of Discussions--Imaging of Drug Use and Abuse | 175 | |
11. | Opening Lecture | |
Relaxation Effects in Spectroscopic Studies of Schizophrenia | 179 | |
12. | Receptor Imaging in Psychiatry--PET, SPECT | |
PET Studies of Dopamine Transmission in Schizophrenia | 186 | |
Neuroreceptor Imaging in Depression | 203 | |
Pharmacologic Imaging of the Dopamine System | 207 | |
Summary of Discussions--Receptor Imaging in Psychiatry--PET, SPECT | 213 | |
13. | Neuropathology in Vivo: MRS | |
Metabolite Mapping in Schizophrenia | 215 | |
Summary of Discussions--Neuropathology in vivo: MRS | 223 | |
14. | The Use of New Structural Imaging Techniques | |
q-Space Diffusion Imaging in Dementia | 224 | |
Magnetization Transfer Imaging in Schizophrenia | 231 | |
Using MTI for the Study of the Neuropathology of Bipolar Disorder | 235 | |
Summary of Discussions--The Use of New Structural Imaging Techniques | 238 | |
15. | The Future | |
What Does Radiology Have to Offer in Psychiatric Neuroimaging in the 21st Century? | 240 | |
Multi-Centre Neuroimaging Studies: Why, (What?) and How? | 245 | |
Summary of Discussions--Round Table and Conclusions | 251 | |
Author Index | 253 |
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