Catecholamine Function in Posttraumatic Stress Disorder: Emerging Concepts Book

Contributors. Introduction to the progress in psychiatry series. Foreword. Introduction. Section I: The Role of Catecholaminergic Systems in Stress Response Syndromes. Biology of catecholaminergic systems and their relevance to PTSD. Locus coeruleus, stress, and PTSD: neurobiological and clinical parallels. Altered electrophysiology of the locus coeruleus following uncontrollable stress: relationship to anxiety and anxiolytic action. Time-dependent change following acute stress: relevance to the chronic and delayed aspects of PTSD. Stressors, the mesocorticolimbic system, and anhedonia: implications for PTSD. Neurobiological mechanisms of PTSD. Section II: Peripheral Autonomic and Catecholamine Function in PTSD. Psychophysiological studies of combat-related PTSD: an integrative review. Basal sympathoadrenal function in patients with PTSD and depression. Stress-induced alterations in plasma catecholamines and sympathetic nervous system function in PTSD. Relationship between catecholamine excretion and PTSD symptoms in Vietnam combat veterans and Holocaust survivors. Plasma norepinephrine and MHPG responses to exercise stress in PTSD. Neurobiological sequelae of childhood trauma: PTSD in children. Peripheral adrenergic receptors in PTSD. Section III: Central Catecholamine Function in PTSD. Neurobiology of startle response abnormalities in PTSD. Use of tricyclics and monoamine oxidase inhibitors in the treatment of PTSD: a quantitative review. Section IV: Methodological Issues. Assessment of sympathetic nervous system function in PTSD: a critique of methodology. Comment: determining the applicability of animal models of stress to the study of PTSD. Afterword. Index.

American Psychiatric Publishing