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Preface: William Slikker, Jr , Russell J. Andrews, and Bruce Trembly.
Part I: Pathophysiology of Nervous System Insults:.
1. Chronic Hypertension Aggravates Heat Stress Induced Cognitive Dysfunction and Brain Pathology: Dafin F. Muresanu and Hari S. Sharma.
2. The Brain as Target for Inflammatory Processes and Neuroprotective Stratagies: Stephen D. Skaper.
3. Genetic and Hormonal Regulation of Tryptophan-Kynurenine Metabolism: Implications for Vascular Cognitive Impairment, Major Depressive Disorder and Aging: Gregory F. Oxenkrug.
4. Metabolic Syndrome in Drug Abuse: Asraf Virmani, Zbigniew K. Binienda, Syed F. Ali and Franco Gaetan.
5. Early Exposure to General Anesthesia Causes Significant Neuronal Deletion in the Developing Rat Brain: H. Nikizad, J-H. Yon, L. B. Carter and V. Jevtovic-Todorovic.
6. Inhibition of T-type Calcium Current in the Reticular Thalamic Nucleus by a Novel Neuroactive Steroid: Pavle M. Joksovic, Douglas F. Covey and Slobodan M. Todorovic.
Part II: Neurotrophic Factors and Neuroprotection.
7. A Select Combination of Neurotrophins Enhances Neuroprotection and Functional Recovery Following Spinal Cord Injury: Hari Shanker Sharma.
8. Intracerebroventricularly-Administered Neurotrophins Attenuate Blood-Cerebrospinal Fluid Barrier Breakdown and Brain Pathology Following Whole Body Hyperthermia: Hari Shanker Sharma and Conrad E. Johanson.
9. Role of Brain-derived Neurotrophic Factor in Neuronal Survival and Behavior-related Plasticity: Robert H. Lipsky and Ann M. Marini.
10. Neurotoxicity of the Human Immunodeficiency Virus Type 1 Protein gp120 in the Rat Nigro-StriatalSystem is Prevented by Brain-Derived Neurotrophic Factor: Italo Mocchetti, Rachel L. Nosheny, Gianluigi Tanda and Edwin M. Meyer.
11. Induction of the Neurotrophic Factors, GDNF and BDNF Associated with the Mechanism of Neurorescue Action of Rasagiline and Ladostigil: New Insights and Implication for Therapy: Orly Weinreb, Tamir Amit, Orit Bar-Am, and Moussa B. H. Youdim.
Part III: Nanotechniques and Neuroprotection:.
12. Neuroprotection at the Nano Level – Part I: An Introduction to Nanoneurosurgery: Russell J. Andrews.
13. Neuroprotection at the Nano Level – Part II: Nanodevices for Neuromodulation - Deep Brain Stimulation and Spinal Cord Injury: Russell J. Andrews.
14. Drug Delivery to the Spinal Cord Tagged with Nanowire Enhances Neuroprotective Efficacy and Functional Recovery Following Trauma to the Rat Spinal Cord: Hari Shanker Sharma, Syed F. Ali, W. Dong, Z. Ryan Tian, R. Patnaik, S. Patnaik, Aruna Sharma, Arne Boman, Per Lek, Elisabeth Seifert and Torbjorn Lundstedt.
15. Treatment of Neurodegenerative Disorders with Radical Nanomedicine: Neeraj Singh, Courtney A. Cohen and Beverly A. Rzigalinski.
Part IV: Additional Approaches to Neuroprotection:.
16. Neuro- and Cardio-protective Effects of Blockade of Nitric Oxide Action by Administration of Methylene Blue: Lars Wiklund, Samar Basu, Adriana Miclescu, Per Wiklund, Gunnar Ronquist and Hari Shanker Sharma.
17. The Effect of Methylene Blue and Related Redox Dyes on MAO Activity, Rat Pineal N-Acetylserotonin, Melatonin, and Related Indoles Content, and on the Righting Reflex in Melatonin-primed Frogs: G.F. Oxenkrug, S.O. Sablin and P.J. Requintina.
18. The Effect of Methyl Derivatives of Dopamine on TNF-alpha and Lipid Peroxidation: Mary C. Perianayagam, Pura J. Requintina, Bertrand L. Jaber and Gregory F. Oxenkrug.
19. Valproate and Acetyl-L-Carnitine Exert a Preventive Action on Methamphetamine-induced Behavioral Sensitization in Mice: Roberto Coccurello, Antonio Caprioli, Orlando Ghirardi and Ashraf Virmani.
20. N-Acetylcysteine Attenuates Arsenite-Induced Oxidative Injury in DRG Explants: P.L. Chao, Y.H. Chou, C.H. Yang and Anya M.Y. Lin.
21. The Effect of Luzindole and other Melatonin Receptor Antagonists on the Iron- and Lipopolysaccharide(LPS)-induced Lipid Peroxidation In Vitro: Pura J. Requintina and Gregory F. Oxenkrug.
22. Antibodies to Serotonin Attenuate Closed Head Injury Induced Blood-Brain Barrier Disruption and Brain Pathology: H.S. Sharma, R. Pataik, S. Mohanty, A. Sharma and V. Prasad.
23. Rab Mediated Endocytosis: Linking Neurodegeneration, Neuroprotection, and Synaptic Plasticity?: A. Baskys, I. Bayazitov, E. Zhu, L. Feng, and R. Wang
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Lynn Bass
reviewed Neuroprotective Agents: Eighth International Neuroprotection Society Meeting on March 21, 2014 Neuroprotective Agents
An ambitious attempt to trace the cognitive steps that led to the modern day human thought form. I was often lost in the density of the material and would've preferred a less verbose extrapolation, though I suppose it was written with a particular audience in mind. Definitely worth multiple reads for those with greater patience.
The focus is mainly forms of communication and symbolic thought. You are guided from mimetic to theoretic culture, ultimately ending on thought that exists as an interplay somewhere between biological organisms and their externally manipulated ideas.
He may have explained why he chose mainly communication as the representation for the development of the mind, though nothing stands out in my memory. As a point of personal conjecture, I believe it was for its utility in expression of deeper cognitive processes and comparative historical and taxonomic referents.
Even with the emphasis on communication and symbols, Donald employs a broad range of studies into his postulates. He presents his ideas methodically and keeps abstraction grounded in empiricism as well as possible given the subject matter. As stated previously, I got lost in the density of some proofs and would, after numerous pages of dissection, forget the original topic of discussion. Even though I feel like his transitions and outlines could be ambiguous, I again refer to the fact that this was probably written to those of the proper frame of reference.
Regardless, he did a very good job considering the subject matter and amount of evidence that needed to be presented.
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