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DNA repair mechanisms Book

DNA repair mechanisms
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  • DNA repair mechanisms
  • Written by author Jean-Michel H. Vos
  • Published by New York : Springer-Verlag ; c1995., 1995/06/01
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Preface
Foreword
1 DNA Damage: Structural and Functional Consequences 1
2 DNA Damage Recognition 25
3 Damage Reversal in Human Cells: Cellular Response to O[superscript 6]-Methylguanine 67
4 Excision Base Repair 99
5 Nucleotide Excision Repair: Molecular and Clinical Implications 125
6 Mismatch Repair and Human Disease 151
7 Intragenomic DNA Repair Heterogeneity 161
8 Endogenous Mutagenesis 175
9 Replication of Genotoxic Lesions: Mechanisms and Medical Impact 187
10 Cell Cycle Checkpoints and Growth-Arrest Genes Activated by Genotoxic Stress 219
11 DNA Repair Deficiency and its Clinical Implication 239
12 Programmed Cell Death 247
13 Loss of Genomic Integrity in Cancer 285
14 Gene Targeting 301
15 DNA Repair Capacity (DRC) as a Biomarker of Human Variational Responses to the Environment 329
16 Radiosensitivity, DNA Double-Strand Break Repair and VDJ Recombination 349
Index 375


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