Free Radicals in Medicine Book

	Forward
Ch. 1	Introduction to Free Radicals	1
1.1	Definition of Free Radicals	1
1.2	Formation of Free Radicals	3
1.3	Dynamics of Free Radical Formation	6
1.4	Methods to Measure Free Radicals	8
Ch. 2	Types of Non-Oxygen Free Radicals	11
2.1	Flavine Semiquinones	11
2.2	Quinones and Semiquinones	16
2.3	Aromatic Compounds	17
2.4	Nucleic Acids	19
2.5	Thylil Radical	20
2.6	Nitric Oxide	21
Ch. 3	Oxygen Free Radicals	23
3.1	The Oxygen Paradox	23
3.2	Singlet Oxygen	25
3.3	Superoxide	26
3.4	Hydrogen Peroxide	28
3.5	Hydroxyl Radical	29
3.6	Peroxides	31
Ch. 4	Natural Processes as Sources of Free Radicals	35
4.1	Mitochondrial Respiration	35
4.2	Peroxisomes	38
4.3	Phagocytosis	40
4.4	Prostaglandins and Leukotrienes	44
4.5	Peroxidation of Unsaturated Lipids	47
4.6	Are Oxygen Free Radicals Chemical Messengers?	51
4.7	Apoptosis	52
Ch. 5	Harmful Effects of Free Radicals	53
5.1	Oxidative Stress	53
5.2	Cell Membrane Damage	58
5.3	Amplifying Factors	61
Ch. 6	Radiation and Free Radicals	71
6.1	UV Radiation	71
6.2	Ionizing Radiation	80
6.3	Eye Diseases	84
Ch. 7	Antioxidants	87
7.1	Introduction to Antioxidants	87
7.2	Natural Antioxidant Enzymes	90
7.3	[publisher omitted]
7.4	Mineral Antioxidants	113
7.5	Plant Antioxidants	116
7.6	Synthetic Antioxidants	118
Ch. 8	Physiologic Effects of Oxygen Stress	119
8.1	Introduction	119
8.2	Pregnancy and the Neonate	119
8.3	Physical and Emotional Stress	120
8.4	Aging	121
8.5	Hyperbaria	126
8.6	Chemical Pollution	127
Ch. 9	Free Radicals and Pathology	129
9.1	Inflammation and Rheumatic Conditions	129
9.2	Cardiovascular Disease	135
9.3	Cancer	142
9.4	Respiratory Failure	144
9.5	Liver Failure	149
9.6	Physiological Brain Diseases	151
9.7	Others	154
Ch. 10	Therapeutic Drugs and Nutrition	157
10.1	Introduction	157
10.2	Prooxidant Drugs	158
10.3	Antioxidant Drugs	160
10.4	Lipids	162
10.5	Free Radicals, Alternative Medicine, and Diet	165
10.6	Antioxidant Therapy	170
	Cited References	173
	Index	185