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Contributors | vii | |
Preface | ix | |
Foreword | xiii | |
1. | An Overview: Molecular Mimicry and Disease | 1 |
2. | Principles of Molecular Mimicry and Autoimmune Disease | 17 |
3. | Molecular Mimicry and Central Nervous System Autoimmune Disease | 27 |
4. | Molecular Mimicry between Streptococcal M Protein and Cardiac Myosin and the Immunopathogenesis of Rheumatic Fever | 39 |
5. | Antigenic Mimicry between Self and Coxsackievirus Proteins Leads to Both Humoral and Cellular Autoimmunity to Heart Proteins | 57 |
6. | Molecular Mimicry and Heart Disease | 69 |
7. | Peptide Mimicry of Streptococcal Group A Carbohydrate | 83 |
8. | Role of Superantigens in Molecular Mimicry and Autoimmunity | 95 |
9. | Peptide Induction of Systemic Lupus Autoimmunity | 109 |
10. | Mimicry between DNA, Carbohydrates, and Peptides: Implications in Systemic Lupus Erythematosus | 127 |
11. | Peptide Mimicry of the Polysaccharide Capsule of Cryptococcus neoformans | 143 |
12. | Autoimmunity in Lyme Arthritis: Molecular Mimicry between OspA and LFA-1 | 161 |
13. | Exploiting Molecular Mimicry in Targeting Carbohydrate Antigens | 175 |
14. | Structural Basis of T-Cell Receptor Specificity and Cross-Reactivity: Implications for the Pathogenesis of Human Autoimmune Diseases | 197 |
15. | Molecular Mimicry and Determinant Spreading | 215 |
16. | Molecular Mimicry: Lessons from Experimental Models of Systemic Lupus Erythematosus and Antiphospholipid Syndrome | 223 |
17. | Contributions of Viruses and Immunity as causes of Diabetes and Development of Strategies for Treatment and Prevention of Autoimmune Disease | 235 |
18. | Molecular Mimicry and Chagas' Disease | 257 |
Color Plates | 275 | |
Index | 279 |
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