Organization of the Prokaryotic Genome Book

	Contributors
	Preface
1	Sequencing Microbial Genomes	1
2	Statistical Predictions of Coding Regions in Prokaryotic Genomes by Using Inhomogeneous Markov Models	11
3	Bacterial Genomes - All Shapes and Sizes	35
4	Archaea: Whose Sister Lineage?	63
5	The Eukaryotic Perspective: Similarities and Distinctions between Pro- and Eukaryotes	77
6	Comparing Microbial Genomes: How the Gene Set Determines the Lifestyle	91
7	Impact of Homologous Recombination on Genome Organization and Stability	109
8	Illegitimate Recombination in Bacteria	129
9	Insertion Sequences and Transposons	151
10	Structure of DNA within the Bacterial Cell: Physics and Physiology	171
11	DNA Supercoiling and Its Consequences for Chromosome Structure and Function	189
12	Local Genetic Context, Supercoiling, and Gene Expression	203
13	"Stable" Genomes	217
14	Unstable Linear Chromosomes: the Case of Streptomyces	235
15	Genomic Flux: Genome Evolution by Gene Loss and Acquisition	263
16	Gene Transfer in Escherichia coli	291
17	Genetic Inventory: Escherichia coli as a Window on Ancestral Proteins	311
18	Proteome Approach to the Identification of Cellular Escherichia coli Proteins	331
19	Genome-Wide Strategies for Studying Gene Function by Using Model Systems	347
	Index	367