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Degenerative Diseases of the Retina Book

Degenerative Diseases of the Retina
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  • Degenerative Diseases of the Retina
  • Written by author Robert E. Anderson
  • Published by Springer-Verlag New York, LLC, 4/30/2013
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1 Apoptosis in Retinitis Pigmentosa 1
2 Oxidative Damage and Responses in Retinal Nuclei Arising from Intense Eight Exposure 9
3 Light-Induced Apoptosis in the Rat Retina in Vivo: Morphological Features, Threshold and Time Course 19
4 Inhibitory Effects of Cycloheximide and Flunarizine on Light-Induced Apoptosis of Photoreceptor Cells 27
5 Apoptosis of Photoreceptors and Lens Fiber Cells with Cataract and Multiple Tumor Formation in the Eyes of Transgenic Mice Lacking the P53 Gene and Expressing the HPV 16 E7 Gene under the Control of the Irbp Promoter 39
6 Function, Age-Related Expression and Molecular Characterization of PEDF, a Neurotrophic Serpin Secreted by Human RPE Cells 51
7 Nitric Oxide in the Retina: Potential Involvement in Retinal Degeneration and Its Control by Growth Factors and Cytokines 61
8 In Vitro Expression of Epidermal Growth Factor Receptor by Human Retinal Pigment Epithelial Cells 69
9 New Retinal Degenerations in the Mouse 77
10 Chorioretinal Interface: Age-Related Changes in Rodent Retina 87
11 Fractionation of Interphotoreceptor Matrix Metalloproteinases 95
12 Peptides from Rhodopsin Induce Experimental Autoimmune Uveoretinitis in Lewis Rats 105
13 Retinal Degeneration in Rat Induced by Vitamin E Deficiency 111
14 Retinal Pigment Epithelial Cells Cultured from RCS Rats Express an Increased Membrane Conductance for Calcium Compared to Normal Rats 119
15 Effect of Sugars on Photoreceptor Outer Segment Assembly 129
16 Regulatory Influences on the Glycosylation of Rhodopsin by Human and Bovine Retinas 139
17 The Dolichol Pathway in the Retinal Pigment Epithelium of the Embryonic Chick 149
18 Morphological and Biochemical Studies of the Retinal Degeneration in the Vitiligo Mouse: A Model with Perturbed Retinoid Metabolism 155
19 Immunological Aspects of Retinal Transplantation in Retinal Degeneration Rodents 163
20 Iron and Hereditary Degeneration of the Retina 177
21 Receptor Degeneration Is a Normal Part of Retinal Development 187
22 Development of Opsin and Synapses in Monkey Photoreceptors 195
23 The Nature of Newly Formed Capillaries in Experimental Naphthalene-Induced Retinal Degeneration in Rabbit 203
24 Retinal Cell Responses to Argon Laser Photocoagulation 209
25 Drosophila as a Model for Photoreceptor Dystrophies and Cell Death 217
26 Abnormal Ca[superscript 2+] Mobilization and Excessive Photopigment Phosphorylation Lead to Photoreceptor Degeneration in Drosophila Mutants 227
27 The Role of Dominant Rhodopsin Mutations in Drosophila Retinal Degeneration 235
28 The Role of the Retinal Degeneration B Protein in the Drosophila Visual System: Function of Drosophila rdgB Protein in Photoreceptors 243
29 Drosophila Visual Transduction, a Model System for Human EYE Disease? Retinal Degenerations 255
30 Characterization of Vertebrate Homologs of Drosophila Photoreceptor Proteins 263
31 Retinal Pathology in Retinitis Pigmentosa: Considerations for Therapy 275
32 Genotype-Phenotype Correlation in Autosomal Dominant Retinal Degeneration with Mutations in the Peripherin/RDS Gene 285
33 Genetic Studies in Autosomal Recessive Forms of Retinitis Pigmentosa
34 Clinical Features of Autosomal Dominant Retinitis Pigmentosa Associated with the Ser 186TRP Mutation of Rhodopsin 303
35 Mutations in the Gene for the B Subunit of Rod Photoreceptor CGMP-Specific Phosphodiesterase (PDEB) in Patients with Retinal Dystrophies and Dysfunctions 313
36 Molecular Genetic Studies of Retinal Dystrophics Principally Affecting the Macula 323
37 Molecular Analysis of the Human GARI Gene: A Candidate Gene for Retinal Degeneration 331
38 Guanylate Cyclase-Activating Protein (GCAP): A Novel Ca[superscript 2+]-Binding Protein in Vertebrate Photoreceptors 339
39 Abnormal Cone Receptor Activity in Patients with Hereditary Degeneration 349
40 Abnormal Rod Photoreceptor Function in Retinitis Pigmentosa 359
41 Scotopic Threshold Responses and Rod Intensity-Response Functions as Sensitive Indicators of the Carrier Status in X-Linked Recessive Retinitis Pigmentosa
42 ERG Findings in Two Patients with Autosomal Dominant Congenital Stationary Night Blindness and HIS258ASN Mutation of the [beta]-Subunit of Rod Photoreceptor CGMP-Specific Phosphodiesterase 377
43 Docosahexaenoic Acid Abnormalities in Red Blood Cells of Patients with Retinitis Pigmentosa 385
44 Ligand-Binding Properties of Recombinant Human IRBP 395
45 Cataractogenesis in Retinitis Pigmentosa: Spectroscopic Fluorescence Analysis of Aqueous Humor Composition 403
Index 409


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