Mathematical Modeling in Nutrition and the Health Sciences Book

	Historical Perspectives and Future Directions
	The Minimal Model of Glucose Regulation: A Biography	1
	Cornerstones to Shape Modeling for the 21[superscript st] Century: Introducing the Aka-Glucose Project	21
	Development and use of Mathematical Models
	Aspects of Effective Modeling	43
	Fitting a Mathematical Model to Biological Data: Intracellular Trafficking in Niemann-Pick C Disease	63
	A Saturation Kinetic Model to Teach Balance of Essential Fatty Acids in Nutrition Education	77
	Theoretical Modeling Issues
	Modeling Processes from Probabilities	87
	Understanding the Relationship Between Carcinogen-Induced DNA Adduct Levels in Distal and Proximal Regions of the Colon	105
	Experimental Aspects of Kinetic Data
	Methodological Issues in Stable Isotope-Based Kinetic Studies in Children	117
	Intrinsic Labeling of Plants for Bioavailability Studies	131
	Elemental Mass Spectrometry for Compartmental Biological Modeling	141
	Modeling of Vitamins, Minerals, and Cholesterol
	The Use of Model-Based Compartmental Analysis to Study Vitamin A Metabolism in a Non-Steady State	159
	Modeling Short (7 Hour)- and Long (6 Week)-Term Kinetics of Vitamin B-6 Metabolism with Stable Isotopes in Humans
	Calcium Utilization in Young Women: New Insights from Modeling	193
	Modeling Cholesterol in Humans: Update and Dealing with the Problem of Exchange In Vivo Using the Blood Cell-Lipoprotein Paradigm	207
	Modeling of Protein Metabolism, Energy, and Growth
	Challenging the Assumptions in Estimating Protein Fractional Synthesis Rate Using a Model of Rodent Protein Turnover	221
	Simulating Patterns of Change in Rates of Secretion of Protein into Milk	239
	Mechanistic Equations to Represent Digestion and Fermentation	253
	Modeling Growth of Cattle for Application within the Structure of the Cornell Net Carbohydrate and Protein System	267
	Modeling to Explore Disease
	Mathematical Models of Tumor Growth: From Empirical Description to Biological Mechanism	287
	A Systems Modeling Approach to the Study of Retinoid Function: Implications for Evaluation of Retinoids in Cancer Chemoprevention and/or Chemotherapy	301
	Glutamate Metabolism in Primary Cultures of Rat Brain Astrocytes: Rationale and Initial Efforts Toward Developing a Compartmental Model	317
	State-of-the-art Modeling Software
	WinSAAM: Application and Explanation	343
	Stata: A Statistical Analysis System for Examining Biomedical Data	353
	Using Advanced Continuous Simulation Language (ACSL) to Simulate, Solve, and Fit Mathematical Models in Nutrition	371
	Solving and Fitting France's Rumen Model with MLAB	389
	Stella Research Software for Teaching Concepts of Nutrient Dynamics in the Undergraduate Classroom	401
	A Review of 'Scientist' Software	407
	Index	415